Literature DB >> 1651707

Transmitter regulation of voltage-dependent K+ channels expressed in Xenopus oocytes.

M P Kavanaugh1, M J Christie, P B Osborne, A E Busch, K Z Shen, Y N Wu, P H Seeburg, J P Adelman, R A North.   

Abstract

Voltage-dependent K+ channels (RBK1, RBK2 and RGK5) were co-expressed in Xenopus oocytes with 5-hydroxytryptamine (5-HT2) receptors. K+ currents measured 2-4 days later were inhibited by 5-HT (100 nM-10 microM, 20-30 s application) by up to 90%. The effect of 5-HT was mimicked by intracellular injection of Ins(1,4,5)P3. Increasing the Ca2+ concentration at the inner surface of excised membrane patches did not decrease the K+ current.

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Year:  1991        PMID： 1651707      PMCID： PMC1151331          DOI： 10.1042/bj2770899

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  30 in total

1.  Patch clamp measurements on Xenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels.

Authors:  C Methfessel; V Witzemann; T Takahashi; M Mishina; S Numa; B Sakmann
Journal:  Pflugers Arch       Date:  1986-12       Impact factor: 3.657

2.  K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.

Authors:  A Wei; M Covarrubias; A Butler; K Baker; M Pak; L Salkoff
Journal:  Science       Date:  1990-05-04       Impact factor: 47.728

3.  Cyclic AMP-dependent protein kinase closes the serotonin-sensitive K+ channels of Aplysia sensory neurones in cell-free membrane patches.

Authors:  M J Shuster; J S Camardo; S A Siegelbaum; E R Kandel
Journal:  Nature       Date:  1985 Jan 31-Feb 6       Impact factor: 49.962

4.  Heteropolymeric potassium channels expressed in Xenopus oocytes from cloned subunits.

Authors:  M J Christie; R A North; P B Osborne; J Douglass; J P Adelman
Journal:  Neuron       Date:  1990-03       Impact factor: 17.173

5.  Cloning of a membrane protein that induces a slow voltage-gated potassium current.

Authors:  T Takumi; H Ohkubo; S Nakanishi
Journal:  Science       Date:  1988-11-18       Impact factor: 47.728

6.  Long-term potentiation of synaptic transmission in the hippocampus induced by a bee venom peptide.

Authors:  E Cherubini; Y Ben Ari; M Gho; J N Bidard; M Lazdunski
Journal:  Nature       Date:  1987 Jul 2-8       Impact factor: 49.962

7.  Rapid and efficient site-specific mutagenesis without phenotypic selection.

Authors:  T A Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

8.  Serotonin receptors expressed in Xenopus oocytes by mRNA from brain mediate a closing of K+ membrane channels.

Authors:  I Parker; M M Panicker; R Miledi
Journal:  Brain Res Mol Brain Res       Date:  1990-01

9.  Mechanism of receptor-mediated modulation of the delayed outward potassium current in guinea-pig ventricular myocytes.

Authors:  K Yazawa; M Kameyama
Journal:  J Physiol       Date:  1990-02       Impact factor: 5.182

10.  Serotonergic modulation of two potassium currents in the pleural sensory neurons of Aplysia.

Authors:  D A Baxter; J H Byrne
Journal:  J Neurophysiol       Date:  1989-09       Impact factor: 2.714
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  4 in total

1.  Serotonin and protein kinase C modulation of a rat brain inwardly rectifying K+ channel expressed in xenopus oocytes.

Authors:  L DiMagno; N Dascal; N Davidson; H A Lester; W Schreibmayer
Journal:  Pflugers Arch       Date:  1996-01       Impact factor: 3.657

2.  Five ADNFLE mutations reduce the Ca2+ dependence of the mammalian alpha4beta2 acetylcholine response.

Authors:  Nivalda Rodrigues-Pinguet; Li Jia; Maureen Li; Antonio Figl; Alwin Klaassen; Anthony Truong; Henry A Lester; Bruce N Cohen
Journal:  J Physiol       Date:  2003-05-16       Impact factor: 5.182

3.  Regulation by second messengers of the slowly activating, voltage-dependent potassium current expressed in Xenopus oocytes.

Authors:  A E Busch; M P Kavanaugh; M D Varnum; J P Adelman; R A North
Journal:  J Physiol       Date:  1992-05       Impact factor: 5.182

Review 4.  5-HT2 receptors-mediated modulation of voltage-gated K+ channels and neurophysiopathological correlates.

Authors:  Maria Cristina D'Adamo; Ilenio Servettini; Luca Guglielmi; Vincenzo Di Matteo; Roberto Di Maio; Giuseppe Di Giovanni; Mauro Pessia
Journal:  Exp Brain Res       Date:  2013-05-24       Impact factor: 1.972
  4 in total

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