| Literature DB >> 16516325 |
Christoph Bremus1, Ute Herrmann, Stephanie Bringer-Meyer, Hermann Sahm.
Abstract
L-Ascorbic acid has been industrially produced for around 70 years. Over the past two decades, several innovative bioconversion systems have been proposed in order to simplify the long time market-dominating Reichstein method, a largely chemical synthesis by which still a considerable part of L-ascorbic acid is produced. Here, we describe the current state of biotechnological alternatives using bacteria, yeasts, and microalgae. We also discuss the potential for direct production of l-ascorbic acid exploiting novel bacterial pathways. The advantages of these novel approaches competing with current chemical and biotechnological processes are outlined.Entities:
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Year: 2006 PMID： 16516325 DOI： 10.1016/j.jbiotec.2006.01.010
Source DB: PubMed Journal: J Biotechnol ISSN： 0168-1656 Impact factor: 3.307