| Literature DB >> 16505319 |
F Schmidt1, J Fischer, U Herrlinger, K Dietz, J Dichgans, M Weller.
Abstract
The authors administered procarbazine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU, lomustine), and vincristine (PCV) to 86 patients with recurrent glioblastoma. There were three partial responses, but no complete responses. Median progression-free survival was 17.1 weeks and progression-free survival at 6 months was 38.4%. World Health Organization grade III/IV hematologic toxicity was common (25.6%), but nonhematologic toxicity was mild.Entities:
Mesh:
Substances:
Year: 2006 PMID: 16505319 DOI: 10.1212/01.wnl.0000197792.73656.c2
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910