Literature DB >> 16499335

Neuroprotective 2-(2-phenylethyl)chromones of Imperata cylindrica.

Jeong Seon Yoon1, Mi Kyeong Lee, Sang Hyun Sung, Young Choong Kim.   

Abstract

Bioactivity-guided fractionation of the methanolic extract of the rhizomes of Imperata cylindrica afforded a new compound, 5-hydroxy-2-(2-phenylethyl)chromone (1), together with three known compounds, 5-hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone (2), flidersiachromone (3), and 5-hydroxy-2-styrylchromone (4). Among these four compounds, 1 and 2 showed significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells.

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Year:  2006        PMID： 16499335     DOI： 10.1021/np0503808

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  14 in total

1.  Monitoring the Chemical Profile in Agarwood Formation within One Year and Speculating on the Biosynthesis of 2-(2-Phenylethyl)Chromones.

Authors:  Ge Liao; Wen-Hua Dong; Jin-Ling Yang; Wei Li; Jun Wang; Wen-Li Mei; Hao-Fu Dai
Journal:  Molecules       Date:  2018-05-25       Impact factor: 4.411

Review 2.  Styrylchromones: Biological Activities and Structure-Activity Relationship.

Authors:  Mariana Lucas; Marisa Freitas; Artur M S Silva; Eduarda Fernandes; Daniela Ribeiro
Journal:  Oxid Med Cell Longev       Date:  2021-12-22       Impact factor: 6.543

3.  5-Hydroxy-2-(2-phenylethyl)chromone (5-HPEC): a novel non-nitrogenous ligand for 5-HT2B receptor.

Authors:  Dwight A Williams; Saheem A Zaidi; Yan Zhang
Journal:  Bioorg Med Chem Lett       Date:  2014-02-19       Impact factor: 2.823

4.  Identification of the protective effects of traditional medicinal plants against SDS-induced Drosophila gut damage.

Authors:  Yang Zhou; Zonglin Liu; Yuchen Chen; Li Hua Jin
Journal:  Exp Ther Med       Date:  2016-08-31       Impact factor: 2.447

5.  Four new compounds from Imperata cylindrica.

Authors:  Xuan Liu; Bin-Feng Zhang; Li Yang; Gui-Xin Chou; Zheng-Tao Wang
Journal:  J Nat Med       Date:  2013-07-20       Impact factor: 2.343

6.  An efficient procedure for the preparation of natural products bearing the 2-(2-phenylethyl)chromone skeleton.

Authors:  Dwight A Williams; Cameron Smith; Yan Zhang
Journal:  Tetrahedron Lett       Date:  2013-08-07       Impact factor: 2.415

7.  Salinity stress induces the production of 2-(2-phenylethyl)chromones and regulates novel classes of responsive genes involved in signal transduction in Aquilaria sinensis calli.

Authors:  Xiaohui Wang; Bowen Gao; Xiao Liu; Xianjuan Dong; Zhongxiu Zhang; Huiyan Fan; Le Zhang; Juan Wang; Shepo Shi; Pengfei Tu
Journal:  BMC Plant Biol       Date:  2016-05-26       Impact factor: 4.215

8.  2-(2-Phenylethyl)chromone Derivatives of Agarwood Originating from Gyrinops salicifolia.

Authors:  Hang Shao; Wen-Li Mei; Wen-Hua Dong; Cui-Juan Gai; Wei Li; Guo-Peng Zhu; Hao-Fu Dai
Journal:  Molecules       Date:  2016-10-03       Impact factor: 4.411

9.  X-ray crystallographic and validated HPTLC analysis of the biomarker chromone glucoside (schumanniofioside A) isolated from Acalypha fruticosa growing in Saudi Arabia.

Authors:  Areej M Al-Taweel; Ghada A Fawzy; Shagufta Perveen; Perwez Alam; Ali A El Gamal
Journal:  Saudi Pharm J       Date:  2017-02-27       Impact factor: 4.330

10.  Phytochemical analysis and in vitro anthelmintic activity of Imperata cylindrica underground parts.

Authors:  Pawi Bawitlung Lalthanpuii; Kholhring Lalchhandama
Journal:  BMC Complement Med Ther       Date:  2020-11-06
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