Literature DB >> 16495272

Molecular characterization of isoniazid resistance in Mycobacterium tuberculosis: identification of a novel mutation in inhA.

E T Y Leung1, P L Ho, K Y Yuen, W L Woo, T H Lam, R Y Kao, W H Seto, W C Yam.   

Abstract

Multiplex allele-specific PCRs detecting katG codon 315 and mabA (bp -15) mutations could specifically identify 77.5% of isoniazid-resistant Mycobacterium tuberculosis strains in the South China region. One clinical isolate harboring InhA Ile194Thr was characterized to show strong association with isoniazid resistance in Mycobacterium tuberculosis.

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Year:  2006        PMID： 16495272      PMCID： PMC1426451          DOI： 10.1128/AAC.50.3.1075-1078.2006

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  20 in total

1.  Usefulness of the MicroSeq 500 16S ribosomal DNA-based bacterial identification system for identification of clinically significant bacterial isolates with ambiguous biochemical profiles.

Authors:  Patrick C Y Woo; Kenneth H L Ng; Susanna K P Lau; Kam-tong Yip; Ami M Y Fung; Kit-wah Leung; Dorothy M W Tam; Tak-lun Que; Kwok-yung Yuen
Journal:  J Clin Microbiol       Date:  2003-05       Impact factor: 5.948

2.  Spread of drug-resistant Mycobacterium tuberculosis strains of the Beijing genotype in the Archangel Oblast, Russia.

Authors:  Olga S Toungoussova; Per Sandven; Andrey O Mariandyshev; Nina I Nizovtseva; Gunnar Bjune; Dominique A Caugant
Journal:  J Clin Microbiol       Date:  2002-06       Impact factor: 5.948

3.  Molecular dynamics simulation studies of the wild-type, I21V, and I16T mutants of isoniazid-resistant Mycobacterium tuberculosis enoyl reductase (InhA) in complex with NADH: toward the understanding of NADH-InhA different affinities.

Authors:  Evelyn Koeche Schroeder; Luiz Augusto Basso; Diógenes Santiago Santos; Osmar Norberto de Souza
Journal:  Biophys J       Date:  2005-05-20       Impact factor: 4.033

4.  Direct detection of rifampin-resistant mycobacterium tuberculosis in respiratory specimens by PCR-DNA sequencing.

Authors:  W C Yam; C M Tam; C C Leung; H L Tong; K H Chan; E T Y Leung; K C Wong; W W Yew; W H Seto; K Y Yuen; P L Ho
Journal:  J Clin Microbiol       Date:  2004-10       Impact factor: 5.948

5.  inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis.

Authors:  A Banerjee; E Dubnau; A Quemard; V Balasubramanian; K S Um; T Wilson; D Collins; G de Lisle; W R Jacobs
Journal:  Science       Date:  1994-01-14       Impact factor: 47.728

6.  The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis.

Authors:  Y Zhang; B Heym; B Allen; D Young; S Cole
Journal:  Nature       Date:  1992-08-13       Impact factor: 49.962

7.  Detection of katG Ser315Thr substitution in respiratory specimens from patients with isoniazid-resistant Mycobacterium tuberculosis using PCR-RFLP.

Authors:  Eric Tung-Yiu Leung; Kai-Man Kam; Agatha Chiu; Pak-Leung Ho; Wing-Hong Seto; Kwok-Yung Yuen; Wing-Cheong Yam
Journal:  J Med Microbiol       Date:  2003-11       Impact factor: 2.472

8.  Inhibition of Mycobacterium tuberculosis AhpD, an element of the peroxiredoxin defense against oxidative stress.

Authors:  Aleksey Koshkin; Xiao-ti Zhou; Carl N Kraus; Jason M Brenner; Pradipta Bandyopadhyay; Irwin D Kuntz; Clifton E Barry; Paul R Ortiz de Montellano
Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191

9.  In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid.

Authors:  Stéphanie Ducasse-Cabanot; Martin Cohen-Gonsaud; Hedia Marrakchi; Michel Nguyen; Didier Zerbib; Jean Bernadou; Mamadou Daffé; Gilles Labesse; Annaïk Quémard
Journal:  Antimicrob Agents Chemother       Date:  2004-01       Impact factor: 5.191

10.  The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance.

Authors:  Richa Rawat; Adrian Whitty; Peter J Tonge
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-17       Impact factor: 11.205
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  12 in total

1.  Evaluation of the AID TB resistance line probe assay for rapid detection of genetic alterations associated with drug resistance in Mycobacterium tuberculosis strains.

Authors:  C Ritter; K Lucke; F A Sirgel; R W Warren; P D van Helden; E C Böttger; G V Bloemberg
Journal:  J Clin Microbiol       Date:  2014-01-08       Impact factor: 5.948

2.  Validation of Novel Mycobacterium tuberculosis Isoniazid Resistance Mutations Not Detectable by Common Molecular Tests.

Authors:  Justin L Kandler; Alexandra D Mercante; Tracy L Dalton; Matthew N Ezewudo; Lauren S Cowan; Scott P Burns; Beverly Metchock; Peter Cegielski; James E Posey
Journal:  Antimicrob Agents Chemother       Date:  2018-09-24       Impact factor: 5.191

3.  Rapid Detection of Mycobacterium tuberculosis Strains Resistant to Isoniazid and/or Rifampicin: Standardization of Multiplex Polymerase Chain Reaction Analysis.

Authors:  Jimena Collantes; Francesca Barletta Solari; Leen Rigouts
Journal:  Am J Trop Med Hyg       Date:  2016-10-24       Impact factor: 2.345

4.  Performance of the genotype MTBDR line probe assay for detection of resistance to rifampin and isoniazid in strains of Mycobacterium tuberculosis with low- and high-level resistance.

Authors:  Florence Brossier; Nicolas Veziris; Chantal Truffot-Pernot; Vincent Jarlier; Wladimir Sougakoff
Journal:  J Clin Microbiol       Date:  2006-10       Impact factor: 5.948

5.  Molecular characterization of fluoroquinolone resistance in Mycobacterium tuberculosis: functional analysis of gyrA mutation at position 74.

Authors:  Ricky W T Lau; Pak-Leung Ho; Richard Y T Kao; Wing-Wai Yew; Terrence C K Lau; Vincent C C Cheng; Kwok-Yung Yuen; Stephen K W Tsui; Xinchun Chen; Wing-Cheong Yam
Journal:  Antimicrob Agents Chemother       Date:  2010-10-18       Impact factor: 5.191

6.  Contribution of dfrA and inhA mutations to the detection of isoniazid-resistant Mycobacterium tuberculosis isolates.

Authors:  Yu Min Ho; Yong-Jiang Sun; Sin-Yew Wong; Ann S G Lee
Journal:  Antimicrob Agents Chemother       Date:  2009-07-06       Impact factor: 5.191

7.  Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis.

Authors:  Diana Machado; David Pires; João Perdigão; Isabel Couto; Isabel Portugal; Marta Martins; Leonard Amaral; Elsa Anes; Miguel Viveiros
Journal:  PLoS One       Date:  2016-02-26       Impact factor: 3.240

8.  Rapid detection of drug-resistant Mycobacterium tuberculosis directly from clinical specimens using allele-specific polymerase chain reaction assay.

Authors:  Pallavi Sinha; Tuhina Banerjee; G N Srivastava; Shampa Anupurba
Journal:  Indian J Med Res       Date:  2019-07       Impact factor: 2.375

9.  Isoniazid inhibits the heme-based reactivity of Mycobacterium tuberculosis truncated hemoglobin N.

Authors:  Paolo Ascenzi; Andrea Coletta; Yu Cao; Viviana Trezza; Loris Leboffe; Gabriella Fanali; Mauro Fasano; Alessandra Pesce; Chiara Ciaccio; Stefano Marini; Massimo Coletta
Journal:  PLoS One       Date:  2013-08-01       Impact factor: 3.240

10.  Genetic and phenotypic characterization of drug-resistant Mycobacterium tuberculosis isolates in Hong Kong.

Authors:  Raphael C Y Chan; Mamie Hui; Edward W C Chan; T K Au; Miu L Chin; Chun K Yip; Carrie K W AuYeang; Christina Y L Yeung; Kai M Kam; Peter C W Yip; Augustine F B Cheng
Journal:  J Antimicrob Chemother       Date:  2007-03-14       Impact factor: 5.790
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