| Literature DB >> 16494944 |
Patricia M B Favaro1, Fabiola Traina, Jose Vassallo, Pierre Brousset, George Delsol, Fernando F Costa, Sara T O Saad.
Abstract
We recently cloned a novel Formin-family human gene, denominated human leukocyte formin and posteriorly named as FMNL1 by the HUGO Gene Nomenclature Committee. This gene is overexpressed in lymphoid malignances and is found associated with Akt. Here, we describe the expression of the FMNL1 protein in 54 frozen biopsies of non-Hodgkin's lymphoma (NHL) patients and five reactive lymph nodes. Western blot analysis revealed expression of FMNL1 in all samples studied, although the highest expression was in T-cell NHL (P<0.05).Entities:
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Year: 2006 PMID： 16494944 DOI： 10.1016/j.leukres.2005.10.003
Source DB: PubMed Journal: Leuk Res ISSN： 0145-2126 Impact factor: 3.156