| Literature DB >> 16494450 |
Kristin N Barlett1, Robert V Kolakowski, Sreenivas Katukojvala, Lawrence J Williams.
Abstract
A one-pot procedure for the conversion of carboxylic acids to N-acyl sulfonamides, via thio acid/azide amidation, is presented. The method is compatible with acid- and base-sensitive amino acid protection. N-Acyl sulfonamide synthesis on solid support, peptide thio acid/sulfonazide coupling, and N-alkyl amide synthesis via selective cleavage of sulfonyl from an N-alkyl-N-acyl sulfonamide are also reported.Entities:
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Year: 2006 PMID： 16494450 DOI： 10.1021/ol052671d
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005