| Literature DB >> 16493415 |
Cullen M Taniguchi1, Brice Emanuelli, C Ronald Kahn.
Abstract
Physiologically important cell-signalling networks are complex, and contain several points of regulation, signal divergence and crosstalk with other signalling cascades. Here, we use the concept of 'critical nodes' to define the important junctions in these pathways and illustrate their unique role using insulin signalling as a model system.Entities:
Mesh：
Substances：
Year: 2006 PMID： 16493415 DOI： 10.1038/nrm1837
Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN： 1471-0072 Impact factor: 94.444