Literature DB >> 16493253

Radical trachelectomy with laparoscopic lymphadenectomy: review of oncologic and obstetrical outcomes.

Alexander F Burnett1.   

Abstract

PURPOSE OF REVIEW: Fertility preservation in early cervical cancer by radical trachelectomy is gaining in acceptance as more cases are published in the literature. Controversies regarding technique and patient management are beginning to emerge as the procedure moves from being a new surgery to a part of standard of care. RECENT
FINDINGS: As the number of cases reported in the literature increases, the effectiveness of radical trachelectomy for treating selected early-stage cancers continues to gain support. The survival of selected patients appears to be no different than that of similar patients treated with radical hysterectomy. Central recurrence in the residual cervix is a very rare event as long as the specimen has cleared the cancer. Patient selection criteria have evolved, and a more liberal use of the procedure is warranted. The effectiveness of trachelectomy in preserving fertility has now been demonstrated in series of 50 and 56 pregnancies occurring after the procedure. These larger series detail pregnancy outcomes and will be invaluable information to our patients who wish to maintain their ability to bear children. Subtle differences in technique between centers may account for different pregnancy outcomes. As more physicians begin to perform radical trachelectomy, controlled trials will be necessary to refine the procedure in order to continue to improve obstetric and oncologic outcomes.
SUMMARY: Radical trachelectomy will continue to increase in popularity as more physicians become willing to learn the technique. It should routinely be offered to young women with early cervix cancer who desire to maintain their fertility.

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Year:  2006        PMID: 16493253     DOI: 10.1097/01.gco.0000192968.75190.dc

Source DB:  PubMed          Journal:  Curr Opin Obstet Gynecol        ISSN: 1040-872X            Impact factor:   1.927


  5 in total

1.  Conservative treatment in early cervical cancer.

Authors:  Mojgan Karimi-Zarchi; Azamsadat Mousavi; Mitra Modares Gilani; Esmat Barooti; Ashrafosadat Miratashi-Yazdi; Atefe Dehghani
Journal:  Int J Biomed Sci       Date:  2013-09

Review 2.  Oncologic and obstetrical outcomes with fertility-sparing treatment of cervical cancer: a systematic review and meta-analysis.

Authors:  Qing Zhang; Wenhui Li; Margaux J Kanis; Gonghua Qi; Minghao Li; Xingsheng Yang; Beihua Kong
Journal:  Oncotarget       Date:  2017-07-11

3.  Discussion of fertility preservation with newly diagnosed patients: oncologists' views.

Authors:  Gwendolyn P Quinn; Susan T Vadaparampil; Clement K Gwede; Cheryl Miree; Lindsey M King; Heather B Clayton; Crystal Wilson; Pamela Munster
Journal:  J Cancer Surviv       Date:  2007-06       Impact factor: 4.062

4.  Fertility-sparing surgery for early-stage cervical cancer.

Authors:  Adelaide Fernanda Ribeiro Cubal; Joana Isabel Ferreira Carvalho; Maria Fernanda Martins Costa; Ana Paula Tavares Branco
Journal:  Int J Surg Oncol       Date:  2012-07-08

5.  Sexual and Reproductive Outcomes in Early Stage Cervical Cancer Patients after Excisional Cone as a Fertility-sparing Surgery: An Italian Experience.

Authors:  Francesco Fanfani; Fabio Landoni; Maria Lucia Gagliardi; Anna Fagotti; Eleonora Preti; Maria Cristina Moruzzi; Giorgia Monterossi; Giovanni Scambia
Journal:  J Reprod Infertil       Date:  2014-01
  5 in total

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