M S Dhillon1, S A Bradley, D W England. 1. Breast Assessment Unit, University Hospital Birmingham NHS Trust, Birmingham Women's Hospital, Edgbaston, Birmingham, UK.
Abstract
AIM: To assess the impact of mammotome biopsy on preoperative diagnosis rate. METHODS: A prospective study was undertaken to examine the referral patterns, radiological abnormalities, sensitivity, specificity and outcome of the first 150 patients undergoing mammotome biopsy at our institution. Most of the referrals were from the NHS Breast Screening Programme (85/100). RESULTS: The commonest radiological abnormality was microcalcification (87%). The accuracy of this biopsy technique for the target lesion was over 99%. Post-biopsy, 11 patients needed to proceed to a diagnostic surgical biopsy (7%). Forty-two malignancies were identified at final histology; 41 were diagnosed preoperatively. The positive predictive of mammotome biopsy was 98% for the present study. The present results for mammotome biopsy with regard to predicting invasion were: sensitivity 71.4% (10/14); specificity 100% (0/0); positive predictive value 100% (10/10); and negative predictive value 87% (27/31). CONCLUSION: Prone mammotome biopsy has proven to be highly accurate, considerably improving the preoperative diagnosis within our unit, and obviating the majority of diagnostic excision biopsies.
AIM: To assess the impact of mammotome biopsy on preoperative diagnosis rate. METHODS: A prospective study was undertaken to examine the referral patterns, radiological abnormalities, sensitivity, specificity and outcome of the first 150 patients undergoing mammotome biopsy at our institution. Most of the referrals were from the NHS Breast Screening Programme (85/100). RESULTS: The commonest radiological abnormality was microcalcification (87%). The accuracy of this biopsy technique for the target lesion was over 99%. Post-biopsy, 11 patients needed to proceed to a diagnostic surgical biopsy (7%). Forty-two malignancies were identified at final histology; 41 were diagnosed preoperatively. The positive predictive of mammotome biopsy was 98% for the present study. The present results for mammotome biopsy with regard to predicting invasion were: sensitivity 71.4% (10/14); specificity 100% (0/0); positive predictive value 100% (10/10); and negative predictive value 87% (27/31). CONCLUSION: Prone mammotome biopsy has proven to be highly accurate, considerably improving the preoperative diagnosis within our unit, and obviating the majority of diagnostic excision biopsies.
Authors: A Luparia; M Durando; P Campanino; E Regini; D Lucarelli; A Talenti; G Mattone; G Mariscotti; A Sapino; G Gandini Journal: Radiol Med Date: 2011-01-12 Impact factor: 3.469
Authors: George C Zografos; Flora Zagouri; Theodoros N Sergentanis; Marios Panou; Dimitrios Dardamanis; Georgia Giannakopoulou; George M Filippakis; George Papadimitriou; Sophia Stamouli Journal: J Med Case Rep Date: 2008-10-17
Authors: George C Zografos; Flora Zagouri; Theodoros N Sergentanis; Dimitra Koulocheri; Afroditi Nonni; Vassiliki Oikonomou; Philip Domeyer; Maria Kotsani; Constantine Fotiadis; John Bramis Journal: World J Surg Oncol Date: 2007-05-14 Impact factor: 2.754
Authors: Flora Zagouri; Theodoros N Sergentanis; Dimitra Koulocheri; Georgia Giannakopoulou; Aphrodite Nonni; Dimitrios Dardamanis; Nikolaos V Michalopoulos; Ioannis Flessas; John Bramis; George C Zografos Journal: J Med Case Rep Date: 2008-05-18