Literature DB >> 16488181

Hydrogen peroxide tooth-whitening (bleaching): review of safety in relation to possible carcinogenesis.

Supritha Naik1, Christopher Jeremy Tredwin, Crispian Scully.   

Abstract

Hydrogen peroxide in the form of carbamide peroxide is widely used in professionally and self-administered products for tooth whitening. Hydrogen peroxide is a highly reactive substance that can damage oral soft and hard tissues when present in high concentrations and with exposures of prolonged duration. This review examines the issue of oral mucosal damage and possible carcinogenicity relating to the use of hydrogen peroxide in the mouth for tooth whitening, with an emphasis on safety with prolonged exposure to low concentrations of peroxide products.

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Year:  2006        PMID: 16488181     DOI: 10.1016/j.oraloncology.2005.10.020

Source DB:  PubMed          Journal:  Oral Oncol        ISSN: 1368-8375            Impact factor:   5.337


  10 in total

1.  Pro-oxidant induced DNA damage in human lymphoblastoid cells: homeostatic mechanisms of genotoxic tolerance.

Authors:  Anna L Seager; Ume-Kulsoom Shah; Jane M Mikhail; Bryant C Nelson; Bryce J Marquis; Shareen H Doak; George E Johnson; Sioned M Griffiths; Paul L Carmichael; Sharon J Scott; Andrew D Scott; Gareth J S Jenkins
Journal:  Toxicol Sci       Date:  2012-04-26       Impact factor: 4.849

Review 2.  Undesirable and adverse effects of tooth-whitening products: a review.

Authors:  Michel Goldberg; Martin Grootveld; Edward Lynch
Journal:  Clin Oral Investig       Date:  2009-06-20       Impact factor: 3.573

3.  Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".

Authors:  Michael P Lisanti; Ubaldo E Martinez-Outschoorn; Zhao Lin; Stephanos Pavlides; Diana Whitaker-Menezes; Richard G Pestell; Anthony Howell; Federica Sotgia
Journal:  Cell Cycle       Date:  2011-08-01       Impact factor: 4.534

4.  Influence of smoking on oral cells genotoxicity after at-home bleaching using 22% carbamide peroxide: a cohort study.

Authors:  Rodrigo Rohenkohl Silva; João Paulo De Carli; Kauê Collares; Júlia Vanini; Júlia Stephenie Presotto; José Eduardo Vargas; Alessandro D Loguercio; Paula Benetti
Journal:  Clin Oral Investig       Date:  2021-08-17       Impact factor: 3.573

5.  Efficacy of whitening oral rinses and dentifrices on color stability of bleached teeth.

Authors:  Muhammet Karadas
Journal:  Acta Biomater Odontol Scand       Date:  2015-04-27

6.  Molecular damage and responses of oral keratinocyte to hydrogen peroxide.

Authors:  Kuan-Yu Lin; Ching-Hung Chung; Jheng-Sian Ciou; Pei-Fang Su; Pei-Wen Wang; Dar-Bin Shieh; Tzu-Chueh Wang
Journal:  BMC Oral Health       Date:  2019-01-11       Impact factor: 2.757

7.  S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide.

Authors:  Christina L Grek; Leticia Reyes; Danyelle M Townsend; Kenneth D Tew
Journal:  BBA Clin       Date:  2014-09-03

8.  The promoting effect of carbamide peroxide teeth bleaching gel in a preclinical model of head and neck cancer in hamster buccal pouch.

Authors:  Vinícius Faccin Bampi; Wadson Ferreira Vilela; Reggiani Vilela Gonçalves; Maria Gabriela Tavares Rheingantz; Luiz Fernando Minello; Jefferson Luis Braga da Silva; Laura Beatriz Oliveira de Oliveira
Journal:  Clin Exp Otorhinolaryngol       Date:  2014-08-01       Impact factor: 3.372

9.  Qualitative study for betel quid cessation among oral cancer patients.

Authors:  Chen-Yi Lee; Chih-Feng Wu; Chun-Ming Chen; Yong-Yuan Chang
Journal:  PLoS One       Date:  2018-07-17       Impact factor: 3.240

10.  A Titanium Tetrafluoride Experimental Gel Combined with Highly Concentrated Hydrogen Peroxide as an Alternative Bleaching Agent: An In Vitro Study.

Authors:  Rodrigo Lins; Pedro Rosalen; Diego Silva; Bianca Kawabata; Luís Roberto Martins; Vanessa Cavalli
Journal:  Gels       Date:  2022-03-14
  10 in total

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