| Literature DB >> 1648612 |
R S Brown1, W T Beaver, W K Bottomley.
Abstract
Proposed mechanisms of the side effect of drug-induced gingival hyperplasia are reviewed. Hypotheses with regard to inflammation from bacterial plaque, increased sulfated glycosaminoglycans, immunoglobulins, gingival fibroblast phenotype population differences, epithelial growth factor, pharmacokinetics and tissuebinding, collagenase activation, disruption of fibroblast cellular sodium/calcium flux, folic acid and a combination hypothesis are evaluated.Entities:
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Year: 1991 PMID： 1648612 DOI： 10.1111/j.1600-0714.1991.tb00419.x
Source DB: PubMed Journal: J Oral Pathol Med ISSN： 0904-2512 Impact factor: 4.253