| Literature DB >> 16478166 |
Zhenxin Wang1, Raphaël Lévy, David G Fernig, Mathias Brust.
Abstract
Peptide-stabilized gold nanoparticles have been enzymatically biotinylated by a kinase-catalyzed reaction using biotin-ATP as a cosubstrate. Upon mixing with avidin-modified particles, solutions of biotinylated particles change color from red to blue, indicating aggregation of particles. On the basis of this reaction, we have developed a simple colorimetric test to monitor kinase inhibitor activity.Entities:
Mesh：
Substances：
Year: 2006 PMID： 16478166 DOI： 10.1021/ja058135y
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419