OBJECTIVE: To report a case of late presentation of alveolar capillary dysplasia and misalignment of pulmonary veins. DESIGN: Descriptive case report. SETTING: Pediatric intensive care unit of a tertiary care children's hospital. PATIENT: Seven-week-old female infant with severe hypoxemic respiratory failure. CONCLUSION: Alveolar capillary dysplasia with misalignment of pulmonary veins is a cause of primary pulmonary hypertension in newborns that can rarely present past the newborn period. Early lung biopsy can be helpful in establishing the diagnosis and avoiding ineffective, futile, and expensive therapeutic interventions.
OBJECTIVE: To report a case of late presentation of alveolar capillary dysplasia and misalignment of pulmonary veins. DESIGN: Descriptive case report. SETTING: Pediatric intensive care unit of a tertiary care children's hospital. PATIENT: Seven-week-old female infant with severe hypoxemic respiratory failure. CONCLUSION:Alveolar capillary dysplasia with misalignment of pulmonary veins is a cause of primary pulmonary hypertension in newborns that can rarely present past the newborn period. Early lung biopsy can be helpful in establishing the diagnosis and avoiding ineffective, futile, and expensive therapeutic interventions.
Authors: Przemyslaw Szafranski; Avinash V Dharmadhikari; Jennifer A Wambach; Chris T Towe; Frances V White; R Mark Grady; Pirooz Eghtesady; F Sessions Cole; Gail Deutsch; Partha Sen; Paweł Stankiewicz Journal: Am J Med Genet A Date: 2014-05-19 Impact factor: 2.802
Authors: Jonathan J Edwards; Chaya Murali; Jennifer Pogoriler; David B Frank; Stephanie S Handler; Mathew A Deardorff; Rachel K Hopper Journal: J Pediatr Date: 2019-03-08 Impact factor: 4.406
Authors: Partha Sen; Avinash V Dharmadhikari; Tadeusz Majewski; Mahmoud A Mohammad; Tanya V Kalin; Joanna Zabielska; Xiaomeng Ren; Molly Bray; Hannah M Brown; Stephen Welty; Sundararajah Thevananther; Claire Langston; Przemyslaw Szafranski; Monica J Justice; Vladimir V Kalinichenko; Anna Gambin; John Belmont; Pawel Stankiewicz Journal: PLoS One Date: 2014-04-10 Impact factor: 3.240