Literature DB >> 16470395

Edematous Schmorl's nodes on thoracolumbar MR imaging: characteristic patterns and changes over time.

Hung-Ta H Wu1, William B Morrison, Mark E Schweitzer.   

Abstract

OBJECTIVE: To describe the patterns and note the evolution of edematous Schmorl's nodes.
MATERIALS AND METHODS: In 47 patients (M:F=26:21, 24-86 years, average 60), 84 Schmorls nodes with T2 hyperintensity with serial MR exams were evaluated. Interval between MR exams was 2-72 months (average 17). Two observers noted size, location, margins, internal and surrounding T1/T2 signal, adjacent disc herniation or bulge, concentric ring, underlying fracture, malignancy, infection, or prior disc surgery, and serial MR changes in these characteristics over time.
RESULTS: Node size averaged 7x9 mm. Most were located at L3 (29%, 24/84), L4 (19%, 16/84) and L2 (13%, 11/84), at the central (39%, 33/84) or outer (30%, 25/84) third of the endplate. 55% (39/71) had a bulging disc, 7% (5/71) had disc herniation. 10% (8/84) had evidence of associated fracture, 17% (14/84) tumor, 7% (6/84) infection. Most nodes had well-defined margins (82%, 69/84). The most common node internal signal was isointense to adjacent disc on T1/T2 (33%, 28/84); surrounding marrow was most commonly hypointense on T1 and hyperintense on T2 (54%, 38/71). A common finding was concentric rings (38%, 32/84) in the marrow surrounding the node, a finding which had 72% negative predictive value for absence of infection, tumor and fracture. On follow-up, there was no interval change in node size in 46%(39/84) of Schmorl's nodes. 26% (22/84) had increased size. Most (60%, 50/84) showed no temporal change in internal T2 signal. 21% (18/84) of nodes showed decreased internal T2 signal, 13% (11/84) showed increased T2 signal. Regarding the surrounding marrow, most (58%, 49/84) showed no temporal change in T2 signal; 21%(18/84) showed decreased T2 signal, 13% (11/84) showed increased T2 signal. In 13 Schmorl's nodes with intranodal enhancement, eight (62%) showed no interval change; among eight with enhancement in surrounding marrow, five (63%) showed no change on follow-up.
CONCLUSION: Although most remain unchanged, a relatively large minority of edematous Schmorl's nodes evolve in size and signal over a relatively short time. Some evolve to form well-defined concentric rings in the surrounding marrow that appear to be analogous to degenerative changes of endplates. Concentric ring formation has a high negative predictive value for "idiopathic" Schmorl's nodes without underlying fracture, infection, or malignancy.

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Mesh:

Year:  2006        PMID: 16470395     DOI: 10.1007/s00256-005-0068-y

Source DB:  PubMed          Journal:  Skeletal Radiol        ISSN: 0364-2348            Impact factor:   2.199


  18 in total

1.  Magnetic resonance imaging of acute intraosseous disc herniation.

Authors:  R Seymour; L A Williams; J I Rees; K Lyons; D C Lloyd
Journal:  Clin Radiol       Date:  1998-05       Impact factor: 2.350

2.  Normal "Cupid's bow" contour of the lower lumbar vertebrae.

Authors:  G W Dietz; E E Christensen
Journal:  Radiology       Date:  1976-12       Impact factor: 11.105

3.  Tunneling Schmorl's nodes.

Authors:  E D Leibner; Y Floman
Journal:  Skeletal Radiol       Date:  1998-04       Impact factor: 2.199

4.  Vertebral end-plate lesions (Schmorl's nodes) in the dorsolumbar spine.

Authors:  R C Hilton; J Ball; R T Benn
Journal:  Ann Rheum Dis       Date:  1976-04       Impact factor: 19.103

5.  Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging.

Authors:  M T Modic; P M Steinberg; J S Ross; T J Masaryk; J R Carter
Journal:  Radiology       Date:  1988-01       Impact factor: 11.105

6.  Relationship of Schmorl's nodes to vertebral body endplate fractures and acute endplate disk extrusions.

Authors:  A L Wagner; F R Murtagh; J A Arrington; D Stallworth
Journal:  AJNR Am J Neuroradiol       Date:  2000-02       Impact factor: 3.825

7.  The pathogenesis of Schmorl's nodes in relation to acute trauma. An autopsy study.

Authors:  V Fahey; K Opeskin; M Silberstein; R Anderson; C Briggs
Journal:  Spine (Phila Pa 1976)       Date:  1998-11-01       Impact factor: 3.468

8.  Schmorl's nodes on magnetic resonance imaging. Their incidence and clinical relevance.

Authors:  C Hamanishi; T Kawabata; T Yosii; S Tanaka
Journal:  Spine (Phila Pa 1976)       Date:  1994-02-15       Impact factor: 3.468

9.  A comparison of radiographic signs of degeneration to corresponding MRI signal intensities in the lumbar spine.

Authors:  D M Marchiori; I McLean; R Firth; R Tatum
Journal:  J Manipulative Physiol Ther       Date:  1994-05       Impact factor: 1.437

Review 10.  Intravertebral disk herniations: cartilaginous (Schmorl's) nodes.

Authors:  D Resnick; G Niwayama
Journal:  Radiology       Date:  1978-01       Impact factor: 11.105

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  22 in total

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Authors:  Cory P Daignault; Edwin L Palmer; James A Scott; John S Swan; Gilbert H Daniels
Journal:  Nucl Med Mol Imaging       Date:  2015-02-03

Review 2.  Schmorl's nodes: current pathophysiological, diagnostic, and therapeutic paradigms.

Authors:  Tobias A Mattei; Azeem A Rehman
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3.  Schmorl's nodes distribution in the human spine and its possible etiology.

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Review 4.  Vertebral endplate signal changes (Modic change): a systematic literature review of prevalence and association with non-specific low back pain.

Authors:  Tue Secher Jensen; Jaro Karppinen; Joan S Sorensen; Jaakko Niinimäki; Charlotte Leboeuf-Yde
Journal:  Eur Spine J       Date:  2008-09-12       Impact factor: 3.134

5.  Follow-up MR imaging of the alar and transverse ligaments after whiplash injury: a prospective controlled study.

Authors:  N Vetti; J Kråkenes; T Ask; K A Erdal; M D N Torkildsen; J Rørvik; N E Gilhus; A Espeland
Journal:  AJNR Am J Neuroradiol       Date:  2011-09-15       Impact factor: 3.825

6.  Endplate changes following discectomy: natural history and associations between imaging and clinical data.

Authors:  Bradley K Weiner; Milorad Vilendecic; Darko Ledic; Sandro Eustacchio; Peter Varga; Miro Gorensek; Joseph Fernandez-Moure; John A Hipp
Journal:  Eur Spine J       Date:  2014-12-28       Impact factor: 3.134

7.  The epidemiology of Schmorl's nodes and their correlation to radiographic degeneration in 4,151 subjects.

Authors:  Stig Sonne-Holm; Steffen Jacobsen; Hans Rovsing; Henrik Monrad
Journal:  Eur Spine J       Date:  2013-03-16       Impact factor: 3.134

8.  Classifications in Brief: Thoracolumbar Injury Classification and Injury Severity Score System.

Authors:  José H Jiménez-Almonte; John D King; T David Luo; R Carter Cassidy; Arun Aneja
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9.  Schmorl Node-A Cause of Acute Thoracic Pain: A Case Report and Pathophysiological Mechanism.

Authors:  Oded Hershkovich; Jonathan E J Koch; Michael P Grevitt
Journal:  Int J Spine Surg       Date:  2020-06-30

10.  Fracture-associated and idiopathic subchondral vertebral lesions: a magnetic resonance study in autopsy specimens with histologic correlation.

Authors:  C A Peters; B C Vande Berg; C Galand; F E Lecouvet; J Malghem
Journal:  Skeletal Radiol       Date:  2008-12-20       Impact factor: 2.199

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