Literature DB >> 32699769

Schmorl Node-A Cause of Acute Thoracic Pain: A Case Report and Pathophysiological Mechanism.

Oded Hershkovich1, Jonathan E J Koch1, Michael P Grevitt1.   

Abstract

PURPOSE: We report a case of a patient with an acute symptomatic Schmorl node (SN) that spontaneously resolved with characteristic imaging findings. The extensive hematological investigations also allow some insight as to the likely pathophysiology of the painful lesion.
METHODS: Case report of an acute symptomatic SN.
RESULTS: A fit and athletic 44-year-old female participant in a competitive paddling event developed atypical thoracic pain and was admitted for further investigation. Normal blood results included complete blood cell count, clotting, and D-dimer. Creatine phosphokinase was 63 U/L (reference < 167 U/L) and troponin I levels were not raised. Her only hematological abnormality was an elevated C-reactive protein (CRP) at 60.2 mg/L (reference < 5 mg/L). Magnetic resonance imaging (MRI) scan showed signal hyperintensity involving T7 vertebral body, surrounding an enlarged SN. Patient was given oral nonsteroidal anti-inflammatory drugs, opioid analgesia, and gradually mobilized. After 3 days, the pain had sufficiently subsided and CRP was 17.8 mg/L. Follow-up MRI scan showed some reduction in the T2 hyperintensity and size of the intraosseous herniation. Patient gradually returned to full activities and had no recurrence of symptoms. MRI scan 8 months after the initial scan showed almost complete resolution of the T2 hyperintensity and pan-vertebral marrow edema.
CONCLUSION: Symptomatic SN should be part of the differential diagnosis of unexplained thoracolumbar pain. Modality of choice for diagnosis would be MRI. Once diagnosed, several treatment options are available with the most likely being spontaneous resolution of symptoms and bone healing within a few months. The conservative approach is recommended when the symptoms can be medically well controlled. ©International Society for the Advancement of Spine Surgery 2020.

Entities:  

Keywords:  Schmorl node; thoracic pain

Year:  2020        PMID: 32699769      PMCID: PMC7343260          DOI: 10.14444/7058

Source DB:  PubMed          Journal:  Int J Spine Surg        ISSN: 2211-4599


  32 in total

Review 1.  Schmorl's nodes.

Authors:  Kwaku A Kyere; Khoi D Than; Anthony C Wang; Shayan U Rahman; Juan M Valdivia-Valdivia; Frank La Marca; Paul Park
Journal:  Eur Spine J       Date:  2012-04-28       Impact factor: 3.134

2.  Prevalence and Clinical Relevance of Schmorl's Nodes on Magnetic Resonance Imaging in a Tertiary Hospital in Southern India.

Authors:  Devimeenal Jagannathan; Venkatraman Indiran; Fouzal Hithaya
Journal:  J Clin Diagn Res       Date:  2016-05-01

3.  Magnetic resonance imaging of acute symptomatic Schmorl's node formation.

Authors:  G Walters; J M Coumas; C M Akins; R L Ragland
Journal:  Pediatr Emerg Care       Date:  1991-10       Impact factor: 1.454

4.  Acute back pain associated with a calcified Schmorl's node: a case report.

Authors:  D M Smith
Journal:  Clin Orthop Relat Res       Date:  1976-06       Impact factor: 4.176

5.  Possible key role of immune system in Schmorl's nodes.

Authors:  Ning Zhang; Fang-Cai Li; Yi-Jiang Huang; Chong Teng; Wei-Shan Chen
Journal:  Med Hypotheses       Date:  2009-10-24       Impact factor: 1.538

6.  Vertebral end-plate lesions (Schmorl's nodes) in the dorsolumbar spine.

Authors:  R C Hilton; J Ball; R T Benn
Journal:  Ann Rheum Dis       Date:  1976-04       Impact factor: 19.103

7.  The epidemiology of Schmorl's nodes and their correlation to radiographic degeneration in 4,151 subjects.

Authors:  Stig Sonne-Holm; Steffen Jacobsen; Hans Rovsing; Henrik Monrad
Journal:  Eur Spine J       Date:  2013-03-16       Impact factor: 3.134

Review 8.  Role of cytokines in bone resorption.

Authors:  G R Mundy
Journal:  J Cell Biochem       Date:  1993-12       Impact factor: 4.429

9.  ISSLS prize winner: prevalence, determinants, and association of Schmorl nodes of the lumbar spine with disc degeneration: a population-based study of 2449 individuals.

Authors:  Florence P S Mok; Dino Samartzis; Jaro Karppinen; Keith D K Luk; Daniel Y T Fong; Kenneth M C Cheung
Journal:  Spine (Phila Pa 1976)       Date:  2010-10-01       Impact factor: 3.468

Review 10.  The role of inflammation in lumbar pain.

Authors:  J S Saal
Journal:  Spine (Phila Pa 1976)       Date:  1995-08-15       Impact factor: 3.468

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  2 in total

1.  Schmorl's Node: An Uncommon Case of Back Pain and Radiculopathy.

Authors:  Allyson Pietrok; Christopher Lee; Rachel J Kaye; Alan D Kaye; George Chesteen
Journal:  Orthop Rev (Pavia)       Date:  2022-04-25

2.  Acute Lumbar Schmorl's Node Following Chiropractic Adjustment.

Authors:  Stephen Albano; Mary Grace Bacani; Anthony Alastra
Journal:  Cureus       Date:  2022-05-22
  2 in total

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