PURPOSE: To investigate direct volumetric in vivo correspondence of calcified atherosclerotic plaque lesions in MRI and CT images of the thoracic aorta by multimodality image registration and fusion. MATERIALS AND METHODS: Twelve CT (11 noncontrast and one contrast) and MRI (TruFISP, contrast T1-weighted volumetric interpolated breath-hold examination (VIBE)) data sets were co-registered by approximate segmentation of the aorta and subsequent automatic co-registration by maximization of mutual information (MI). We quantitatively assessed 22 co-registered calcified plaque lesions on CT and MRI. RESULTS: The three-dimensional registration consistency and accuracy were 1.74 +/- 1.3 mm, and 2.42 +/- 1.65 mm, respectively. The ratio of CT/MRI calcified plaque volume decreased asymptotically with MRI volume, and correlated with average CT lesion density (r = 0.72) for small lesions (<25 mm(3)). The average calcified plaque volume, circumferential extent, and maximal radial width by MRI were significantly smaller compared to CT (35%, 68%, and 53%, respectively; P < 0.05). CONCLUSION: Software co-registration allowed precise, direct, and voxel-based comparison of calcified atherosclerotic plaque lesions imaged by MRI and CT. In comparison with co-registered MRI, overestimation of calcified plaque in aortic CT due to "blooming" correlates with the average lesion density for small plaques, and is greater for small plaques. (c) 2006 Wiley-Liss, Inc.
PURPOSE: To investigate direct volumetric in vivo correspondence of calcified atherosclerotic plaque lesions in MRI and CT images of the thoracic aorta by multimodality image registration and fusion. MATERIALS AND METHODS: Twelve CT (11 noncontrast and one contrast) and MRI (TruFISP, contrast T1-weighted volumetric interpolated breath-hold examination (VIBE)) data sets were co-registered by approximate segmentation of the aorta and subsequent automatic co-registration by maximization of mutual information (MI). We quantitatively assessed 22 co-registered calcified plaque lesions on CT and MRI. RESULTS: The three-dimensional registration consistency and accuracy were 1.74 +/- 1.3 mm, and 2.42 +/- 1.65 mm, respectively. The ratio of CT/MRI calcified plaque volume decreased asymptotically with MRI volume, and correlated with average CT lesion density (r = 0.72) for small lesions (<25 mm(3)). The average calcified plaque volume, circumferential extent, and maximal radial width by MRI were significantly smaller compared to CT (35%, 68%, and 53%, respectively; P < 0.05). CONCLUSION: Software co-registration allowed precise, direct, and voxel-based comparison of calcified atherosclerotic plaque lesions imaged by MRI and CT. In comparison with co-registered MRI, overestimation of calcified plaque in aortic CT due to "blooming" correlates with the average lesion density for small plaques, and is greater for small plaques. (c) 2006 Wiley-Liss, Inc.
Authors: Bernard C M te Boekhorst; Maarten J Cramer; Gerard Pasterkamp; Cees J A van Echteld; Pieter A F M Doevendans Journal: Int J Cardiovasc Imaging Date: 2010-01-29 Impact factor: 2.357
Authors: R Zainon; J P Ronaldson; T Janmale; N J Scott; T M Buckenham; A P H Butler; P H Butler; R M Doesburg; S P Gieseg; J A Roake; N G Anderson Journal: Eur Radiol Date: 2012-07-04 Impact factor: 5.315
Authors: Tobias Penzkofer; Eva Donandt; Peter Isfort; Thomas Allmendinger; Christiane K Kuhl; Andreas H Mahnken; Philipp Bruners Journal: BMC Med Imaging Date: 2014-09-01 Impact factor: 1.930