Literature DB >> 16463161

Antibiotic production by actinomycetes: the Janus faces of regulation.

Eric Cundliffe1.   

Abstract

This manuscript reviews some of the common regulatory mechanisms that control antibiotic production in actinomycetes. These ubiquitous bacteria, collectively responsible for the earthy smell of soil, are prolific producers of antibiotics and other secondary metabolites. The content of this review is biased towards the author's current research interests, concerning the action of regulatory gene products that control transcription of antibiotic-biosynthetic genes and the associated involvement of low molecular weight signalling molecules of the gamma-butyrolactone family. As a result, much fertile ground remains unturned particularly in the area of environmental monitoring and responses of actinomycetes to stimuli so perceived. Reviews casting a broader net are cited in the text.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16463161     DOI： 10.1007/s10295-006-0083-6

Source DB:  PubMed          Journal:  J Ind Microbiol Biotechnol        ISSN： 1367-5435            Impact factor:   3.346


  33 in total

1.  Inactivation of a transcriptional repressor during empirical improvement of the tylosin producer, Streptomyces fradiae.

Authors:  G Stratigopoulos; E Cundliffe
Journal:  J Ind Microbiol Biotechnol       Date:  2002-04       Impact factor: 3.346

2.  Expression analysis of the tylosin-biosynthetic gene cluster: pivotal regulatory role of the tylQ product.

Authors:  George Stratigopoulos; Eric Cundliffe
Journal:  Chem Biol       Date:  2002-01

Review 3.  Regulation of secondary metabolism in streptomycetes.

Authors:  Mervyn J Bibb
Journal:  Curr Opin Microbiol       Date:  2005-04       Impact factor: 7.934

Review 4.  1995 Colworth Prize Lecture. The regulation of antibiotic production in Streptomyces coelicolor A3(2).

Authors:  Mervyn Bibb
Journal:  Microbiology (Reading)       Date:  1996-06       Impact factor: 2.777

5.  CcaR is an autoregulatory protein that binds to the ccaR and cefD-cmcI promoters of the cephamycin C-clavulanic acid cluster in Streptomyces clavuligerus.

Authors:  Irene Santamarta; Antonio Rodríguez-García; Rosario Pérez-Redondo; Juan F Martín; Paloma Liras
Journal:  J Bacteriol       Date:  2002-06       Impact factor: 3.490

Review 6.  Control of antibiotic biosynthesis.

Authors:  J F Martin; A L Demain
Journal:  Microbiol Rev       Date:  1980-06

7.  The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces.

Authors:  M A Fernández-Moreno; J L Caballero; D A Hopwood; F Malpartida
Journal:  Cell       Date:  1991-08-23       Impact factor: 41.582

8.  Gene replacement analysis of the Streptomyces virginiae barA gene encoding the butyrolactone autoregulator receptor reveals that BarA acts as a repressor in virginiamycin biosynthesis.

Authors:  H Nakano; E Takehara; T Nihira; Y Yamada
Journal:  J Bacteriol       Date:  1998-07       Impact factor: 3.490

9.  The regulator of streptomycin gene expression, StrR, of Streptomyces griseus is a DNA binding activator protein with multiple recognition sites.

Authors:  L Retzlaff; J Distler
Journal:  Mol Microbiol       Date:  1995-10       Impact factor: 3.501

10.  A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor.

Authors:  Eriko Takano; Hiroshi Kinoshita; Vassilis Mersinias; Giselda Bucca; Graham Hotchkiss; Takuya Nihira; Colin P Smith; Mervyn Bibb; Wolfgang Wohlleben; Keith Chater
Journal:  Mol Microbiol       Date:  2005-04       Impact factor: 3.501
View more
  8 in total

1.  Characterization of the biosynthetic gene cluster (ata) for the A201A aminonucleoside antibiotic from Saccharothrix mutabilis subsp. capreolus.

Authors:  Irene Saugar; Brian Molloy; Eloisa Sanz; María Blanca Sánchez; María Fernández-Lobato; Antonio Jiménez
Journal:  J Antibiot (Tokyo)       Date:  2016-10-12       Impact factor: 2.649

2.  A Complex Signaling Cascade Governs Pristinamycin Biosynthesis in Streptomyces pristinaespiralis.

Authors:  Yvonne Mast; Jamil Guezguez; Franziska Handel; Eva Schinko
Journal:  Appl Environ Microbiol       Date:  2015-07-17       Impact factor: 4.792

3.  Variation in Metabolite Profiles of Amphibian Skin Bacterial Communities Across Elevations in the Neotropics.

Authors:  Daniel Medina; Myra C Hughey; Matthew H Becker; Jenifer B Walke; Thomas P Umile; Elizabeth A Burzynski; Anthony Iannetta; Kevin P C Minbiole; Lisa K Belden
Journal:  Microb Ecol       Date:  2017-01-19       Impact factor: 4.552

4.  Characterization of the gut microbiota in the golden takin (Budorcas taxicolor bedfordi).

Authors:  Jun Chen; Huanxin Zhang; Xiaoyang Wu; Shuai Shang; Jiakuo Yan; Yao Chen; Honghai Zhang; Xuexi Tang
Journal:  AMB Express       Date:  2017-04-17       Impact factor: 3.298

5.  Structure of an MmyB-like regulator from C. aurantiacus, member of a new transcription factor family linked to antibiotic metabolism in actinomycetes.

Authors:  Qingping Xu; Gilles P van Wezel; Hsiu-Ju Chiu; Lukasz Jaroszewski; Heath E Klock; Mark W Knuth; Mitchell D Miller; Scott A Lesley; Adam Godzik; Marc-André Elsliger; Ashley M Deacon; Ian A Wilson
Journal:  PLoS One       Date:  2012-07-26       Impact factor: 3.240

6.  Cool temperatures reduce antifungal activity of symbiotic bacteria of threatened amphibians--implications for disease management and patterns of decline.

Authors:  Joshua H Daskin; Sara C Bell; Lin Schwarzkopf; Ross A Alford
Journal:  PLoS One       Date:  2014-06-18       Impact factor: 3.240

7.  Coral-Associated Actinobacteria: Diversity, Abundance, and Biotechnological Potentials.

Authors:  Huda M Mahmoud; Aisha A Kalendar
Journal:  Front Microbiol       Date:  2016-02-29       Impact factor: 5.640

8.  Comparative Analysis of the Fecal Bacterial Microbiota of Wintering Whooper Swans (Cygnus Cygnus).

Authors:  Wenxia Wang; Songlin Huang; Liangliang Yang; Guogang Zhang
Journal:  Front Vet Sci       Date:  2021-07-12
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.