| Literature DB >> 16458941 |
Abstract
A compound that inhibited angiotensin-I converting enzyme (ACE) activity was isolated from buckwheat powder. This compound is thought to be the hydroxy derivative of nicotianamine and its chemical structure is 2''-hydroxynicotianamine. This compound showed a very high inhibitory activity toward ACE, and the IC(50) was 0.08 microM. Only this hydroxy analog was found in buckwheat powder, at about 30 mg/100g, and no nicotianamine was detected. However, nicotianamine was detected in the buckwheat plant body. 2''-hydroxynicotianamine was also found in other polygonaceous plants.Entities:
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Year: 2006 PMID： 16458941 DOI： 10.1016/j.phytochem.2005.12.022
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072