Literature DB >> 16456111

Early growth response-1 in cardiovascular pathobiology.

Levon M Khachigian1.   

Abstract

The immediate-early gene product and zinc finger transcription factor early growth response (Egr)-1 plays a key master regulatory role in multiple cardiovascular pathological processes. This article reviews the amazing recent evidence implicating Egr-1 in atherosclerosis, intimal thickening after acute vascular injury, ischemic pathology, angiogenesis, allograft rejection, and cardiac hypertrophy.

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Year:  2006        PMID： 16456111     DOI： 10.1161/01.RES.0000200177.53882.c3

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


  96 in total

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9.  Early Growth Response 1 (Egr-1) Is a Transcriptional Activator of β-Secretase 1 (BACE-1) in the Brain.

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