Literature DB >> 16453733

suc1 is an essential gene involved in both the cell cycle and growth in fission yeast.

J Hayles1, S Aves, P Nurse.   

Abstract

The gene suc1 encodes a product which suppresses certain temperature sensitive mutants of the cell cycle control gene cdc2 of Schizosaccharomyces pombe. Mutants in the suc1 gene or over-expression of its product leads to delays in mitotic and meiotic nuclear division. Deletion of the suc1 gene is lethal and generates some cells blocked in the cell cycle and others impaired in cellular growth. It is likely that the suc1 gene product binds and forms unstable complexes with the cdc2 protein kinase and with other proteins necessary for the cell cycle and cellular growth. suc1 may have a regulatory role in these processes.

Entities:  

Year:  1986        PMID: 16453733      PMCID: PMC1167336          DOI: 10.1002/j.1460-2075.1986.tb04653.x

Source DB:  PubMed          Journal:  EMBO J        ISSN: 0261-4189            Impact factor:   11.598


  18 in total

1.  Conditional-lethal mutations that suppress genetic defects in morphogenesis by altering structural proteins.

Authors:  J Jarvik; D Botstein
Journal:  Proc Natl Acad Sci U S A       Date:  1975-07       Impact factor: 11.205

2.  Genetic control of cell size at cell division in yeast.

Authors:  P Nurse
Journal:  Nature       Date:  1975-08-14       Impact factor: 49.962

Review 3.  Mechanisms of suppression.

Authors:  P E Hartman; J R Roth
Journal:  Adv Genet       Date:  1973       Impact factor: 1.944

4.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1983-07-01       Impact factor: 3.365

5.  Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

Authors:  G K McMaster; G G Carmichael
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

6.  The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function.

Authors:  J Hayles; D Beach; B Durkacz; P Nurse
Journal:  Mol Gen Genet       Date:  1986-02

7.  Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe.

Authors:  P Nurse; P Thuriaux; K Nasmyth
Journal:  Mol Gen Genet       Date:  1976-07-23

8.  Regulatory genes controlling mitosis in the fission yeast Schizosaccharomyces pombe.

Authors:  P Nurse; P Thuriaux
Journal:  Genetics       Date:  1980-11       Impact factor: 4.562

9.  Fission yeast Schizosaccharomyces pombe correctly excises a mammalian RNA transcript intervening sequence.

Authors:  N F Käufer; V Simanis; P Nurse
Journal:  Nature       Date:  1985 Nov 7-13       Impact factor: 49.962

10.  Ascospore development in the fission yeasts Schizosaccharomyces pombe and S. japonicus.

Authors:  K Tanaka; A Hirata
Journal:  J Cell Sci       Date:  1982-08       Impact factor: 5.285

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  53 in total

Review 1.  Regulation of cyclin-dependent kinases in Arabidopsis thaliana.

Authors:  H Stals; P Casteels; M Van Montagu; D Inzé
Journal:  Plant Mol Biol       Date:  2000-08       Impact factor: 4.076

2.  Isolation and characterization of temperature-sensitive mutations in the RAS2 and CYR1 genes of Saccharomyces cerevisiae.

Authors:  H Mitsuzawa; I Uno; T Oshima; T Ishikawa
Journal:  Genetics       Date:  1989-12       Impact factor: 4.562

3.  Regulation of a Myb transcription factor by cyclin-dependent kinase 2 in Giardia lamblia.

Authors:  Chao-Cheng Cho; Li-Hsin Su; Yu-Chang Huang; Yu-Jiao Pan; Chin-Hung Sun
Journal:  J Biol Chem       Date:  2011-12-13       Impact factor: 5.157

4.  Cold-sensitive mutants of p34cdc2 that suppress a mitotic catastrophe phenotype in fission yeast.

Authors:  K Ayscough; J Hayles; S A MacNeill; P Nurse
Journal:  Mol Gen Genet       Date:  1992-04

5.  A dominant negative allele of p34cdc2 shows altered phosphoamino acid content and sequesters p56cdc13 cyclin.

Authors:  U N Fleig; K L Gould; P Nurse
Journal:  Mol Cell Biol       Date:  1992-05       Impact factor: 4.272

Review 6.  Gene overexpression: uses, mechanisms, and interpretation.

Authors:  Gregory Prelich
Journal:  Genetics       Date:  2012-03       Impact factor: 4.562

7.  Dissociation of meiotic and mitotic roles of the fission yeast cdc2 gene.

Authors:  B Grallert; M Sipiczki
Journal:  Mol Gen Genet       Date:  1990-07

8.  The Prozone Effect Accounts for the Paradoxical Function of the Cdk-Binding Protein Suc1/Cks.

Authors:  Sang Hoon Ha; Sun Young Kim; James E Ferrell
Journal:  Cell Rep       Date:  2016-02-04       Impact factor: 9.423

9.  Pachytene arrest and other meiotic effects of the start mutations in Saccharomyces cerevisiae.

Authors:  E O Shuster; B Byers
Journal:  Genetics       Date:  1989-09       Impact factor: 4.562

10.  CKS1BP7, a Pseudogene of CKS1B, is Co-Amplified with IGF1R in Breast Cancers.

Authors:  Yansong Liu; Wei Wang; Yan Li; Feifei Sun; Jiaxiang Lin; Li Li
Journal:  Pathol Oncol Res       Date:  2017-04-24       Impact factor: 3.201

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