Literature DB >> 16449392

Diabetes: how are we diagnosing and initially managing it?

Patrick J O'Connor1, Edward Gregg, William A Rush, Linda M Cherney, Michael N Stiffman, Michael M Engelgau.   

Abstract

PURPOSE: We undertook this study to examine the symptoms, clinical events, and types of health care encounters that preceded the diagnosis of diabetes mellitus in adults, and to examine changes in glycemic control and cardiovascular risk factors in the first year after a diabetes diagnosis.
METHODS: We conducted a historical cohort study of patients in a large multispecialty medical group in Minnesota. Among 55,121 adults who were continuously enrolled in the health plan and receiving care at the study medical group from January 1, 1993, to December 31, 1996, we identified 504 who received a new diagnosis of diabetes in 1995 or 1996. Our main outcome measures were the type of symptoms at diagnosis; the clinical circumstances and type of encounter that led to diabetes diagnosis; and changes in glycemic control (assessed by hemoglobin A1c [HbA1c] value), low-density lipoprotein cholesterol level, blood pressure (BP), aspirin use, and body weight in the first year after diagnosis, ascertained from a detailed review of medical records.
RESULTS: Almost one third (32.3%) of adults with newly diagnosed diabetes had symptoms of hyperglycemia at initial diagnosis. Compared with patients who did not have hyperglycemia symptoms at diagnosis, those who did were younger and more often male, and had lower comorbidity scores and higher HbA1c values (9.9% vs 8.1%) at diagnosis (P <.01 for each comparison). In the 12 months after diagnosis, the group as a whole had significant improvements (P <.001) in HbA1c values (from 8.8% to 7.1%), systolic blood pressure (137.5 to 133.2 mm Hg), diastolic blood pressure (80.7 to 77.3 mm Hg), weight (207.7 to 201.1 lb), and aspirin use (15.3% to 26.1%). Improvements were seen in all patient subgroups, including those defined by symptoms at diagnosis and by visit type at diagnosis.
CONCLUSIONS: Primary care practices may improve detection of undiagnosed diabetes in primary care and improve 1-year outcomes by being vigilant for symptoms of diabetes, by evaluating those at high risk for this disorder, and by instituting appropriate treatments at the time of diagnosis.

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Year:  2006        PMID: 16449392      PMCID: PMC1466993          DOI: 10.1370/afm.419

Source DB:  PubMed          Journal:  Ann Fam Med        ISSN: 1544-1709            Impact factor:   5.166


  37 in total

1.  Finding undiagnosed type 2 diabetes: is it worth the effort?

Authors:  M M Engelgau; K M Narayan
Journal:  Eff Clin Pract       Date:  2001 Nov-Dec

2.  Improving diabetes care in a large health care system: an enhanced primary care approach.

Authors:  J Sperl-Hillen; P J O'Connor; R R Carlson; T B Lawson; C Halstenson; T Crowson; J Wuorenma
Journal:  Jt Comm J Qual Improv       Date:  2000-11

3.  Factors driving diabetes care improvement in a large medical group: ten years of progress.

Authors:  JoAnn M Sperl-Hillen; Patrick J O'Connor
Journal:  Am J Manag Care       Date:  2005-08       Impact factor: 2.229

4.  The continuing epidemics of obesity and diabetes in the United States.

Authors:  A H Mokdad; B A Bowman; E S Ford; F Vinicor; J S Marks; J P Koplan
Journal:  JAMA       Date:  2001-09-12       Impact factor: 56.272

5.  Screening for diabetes in general practice: cross sectional population study.

Authors:  J M Lawrence; P Bennett; A Young; A M Robinson
Journal:  BMJ       Date:  2001-09-08

6.  Screening for diabetes mellitus in high-risk patients: cost, yield, and acceptability.

Authors:  P J O'Connor; W A Rush; L M Cherney; N P Pronk
Journal:  Eff Clin Pract       Date:  2001 Nov-Dec

7.  Screening for type 2 diabetes mellitus in adults: recommendations and rationale.

Authors: 
Journal:  Ann Intern Med       Date:  2003-02-04       Impact factor: 25.391

Review 8.  Screening adults for type 2 diabetes: a review of the evidence for the U.S. Preventive Services Task Force.

Authors:  Russell Harris; Katrina Donahue; Saif S Rathore; Paul Frame; Steven H Woolf; Kathleen N Lohr
Journal:  Ann Intern Med       Date:  2003-02-04       Impact factor: 25.391

9.  Quality of care for patients diagnosed with diabetes at screening.

Authors:  David Edelman; Maren K Olsen; Tara K Dudley; Amy C Harris; Eugene Z Oddone
Journal:  Diabetes Care       Date:  2003-02       Impact factor: 19.112

10.  Elevated risk of cardiovascular disease prior to clinical diagnosis of type 2 diabetes.

Authors:  Frank B Hu; Meir J Stampfer; Steven M Haffner; Caren G Solomon; Walter C Willett; JoAnn E Manson
Journal:  Diabetes Care       Date:  2002-07       Impact factor: 19.112

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  10 in total

1.  International challenges without borders: a descriptive study of family physicians' educational needs in the field of diabetes.

Authors:  Suzanne Murray; Patrice Lazure; Sara Schroter; Philipp J Leuschner; Peter Posel; Thomas Kellner; Richard D Jenkins
Journal:  BMC Fam Pract       Date:  2011-05-11       Impact factor: 2.497

2.  The relative contribution of patient, provider and organizational influences to the appropriate diagnosis and management of diabetes mellitus.

Authors:  Lisa Marceau; John McKinlay; Rebecca Shackelton; Carol Link
Journal:  J Eval Clin Pract       Date:  2010-07-13       Impact factor: 2.431

3.  The growing importance of diabetes screening.

Authors:  Todd P Gilmer; Patrick J O'Connor
Journal:  Diabetes Care       Date:  2010-07       Impact factor: 17.152

4.  Quality of care for first-degree relatives of type 2 diabetes patients diagnosed with diabetes at a screening program one year after diagnosis.

Authors:  Massoud Amini; Azam Timori; Ashraf Aminorroaya
Journal:  Rev Diabet Stud       Date:  2008-05-10

5.  Presenting features of diabetes mellitus.

Authors:  M Emmanuel Bhaskar; G Sowmya; Swathy Moorthy; N Senthil Kumar; R Praveena; Vinod Kumar
Journal:  Indian J Community Med       Date:  2010-10

6.  The effect of quality of care on cardiovascular risk factors in newly diagnosed diabetic patients.

Authors:  Azam Teimouri; Bijan Iraj; Massoud Amini; Silva Hovsepian
Journal:  Int J Prev Med       Date:  2014-11

7.  An opportunistic pre-diabetes screening program offered with existing hypertension screening.

Authors:  M T Iqbal
Journal:  J Prev Med Hyg       Date:  2013-03

8.  Identifying gaps in the continuum of care for cardiovascular disease and diabetes in two communities in South Africa: Baseline findings from the HealthRise project.

Authors:  Alexandra Wollum; Rose Gabert; Claire R McNellan; Jessica M Daly; Priscilla Reddy; Paurvi Bhatt; Miranda Bryant; Danny V Colombara; Pamela Naidoo; Belinda Ngongo; Anam Nyembezi; Zaino Petersen; Bryan Phillips; Shelley Wilson; Emmanuela Gakidou; Herbert C Duber
Journal:  PLoS One       Date:  2018-03-14       Impact factor: 3.240

9.  Trends in Method of Diagnosis of Type 2 Diabetes Mellitus: Results from SHIELD.

Authors:  Helena W Rodbard; Andrew J Green; Kathleen M Fox; Susan Grandy
Journal:  Int J Endocrinol       Date:  2009       Impact factor: 3.257

Review 10.  Systematic review and meta-analysis of validation studies on a diabetes case definition from health administrative records.

Authors:  Aaron Leong; Kaberi Dasgupta; Sasha Bernatsky; Diane Lacaille; Antonio Avina-Zubieta; Elham Rahme
Journal:  PLoS One       Date:  2013-10-09       Impact factor: 3.240

  10 in total

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