Literature DB >> 16449104

Management of cervical insufficiency and bulging fetal membranes.

George Daskalakis1, Nikolaos Papantoniou, Spiros Mesogitis, Aris Antsaklis.   

Abstract

OBJECTIVE: To evaluate the efficacy of emergency cerclage in cases with dilated cervix and protruding fetal membranes in a group of women considered at low risk for preterm delivery by their obstetric histories.
METHODS: All cases of cervical dilatation and bulging membranes were detected through a transvaginal ultrasonographic screening for preterm delivery between 18 and 26 weeks during a 6-year study period. Twenty-nine women underwent an emergency cervical cerclage and composed the cerclage group, whereas 17 others refused and formed the bed rest group. All patients were given antibiotics and prophylactic tocolysis.
RESULTS: The mean prolongation of pregnancy (8.8 weeks) and the mean birth weight (2,101 g) after cerclage placement differed significantly from those of the bed rest group (3.1 weeks and 739 g, respectively). Twenty-five of the 29 pregnancies in the cerclage group ended in live birth, compared with 7 of the 17 pregnancies in the bed rest group (P = .001) (relative risk [RR] 0.33, 95% confidence interval [CI] 0.11-0.98). Neonatal survival was 96% in the cerclage group and 57.1% in the bed rest group (P = .025) (RR 0.09, 95% CI 0.01-0.76). The preterm delivery rate less than 32 weeks was 31% and 94.1% in the cerclage and the bed rest groups, respectively (P < .001) (RR 0.33, 95% CI 0.19-0.57), whereas the admission to neonatal intensive care unit was 28% and 85.7% in the 2 groups, respectively, (P = .01) (RR 0.33, 95% CI 0.16-0.66).
CONCLUSION: Emergency cervical cerclage can be accomplished safely in women with dilated cervix and bulging membranes. It can reduce preterm delivery before 32 weeks and improve neonatal survival compared with bed rest. LEVEL OF EVIDENCE: II-1.

Entities:  

Mesh:

Year:  2006        PMID: 16449104     DOI: 10.1097/01.AOG.0000187896.04535.e6

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN: 0029-7844            Impact factor:   7.661


  27 in total

1.  Injectable silk-based biomaterials for cervical tissue augmentation: an in vitro study.

Authors:  Joseph E Brown; Benjamin P Partlow; Alison M Berman; Michael D House; David L Kaplan
Journal:  Am J Obstet Gynecol       Date:  2015-08-24       Impact factor: 8.661

2.  A comparison of pregnancy outcome of emergency modified transvaginal cervicoisthmic cerclage performed in twin and singleton pregnancies.

Authors:  Minling Wei; Yang Yang; Xiaoying Jin; Jingyan Yang; Dong Huang; Songying Zhang
Journal:  Arch Gynecol Obstet       Date:  2021-01-02       Impact factor: 2.344

3.  Delayed interval delivery in a triplet gestation.

Authors:  Rachel J Wooldridge; Emily A Oliver; Tulika Singh
Journal:  BMJ Case Rep       Date:  2012-11-27

4.  Is Uterocervical Angle Associated with Gestational Latency after Physical Exam Indicated Cerclage?

Authors:  Kate Swanson; William A Grobman; Emily S Miller
Journal:  Am J Perinatol       Date:  2018-01-24       Impact factor: 1.862

5.  Physical examination-indicated cerclage in twin pregnancy: a retrospective cohort study.

Authors:  Mian Pan; Jun Zhang; Wenqiang Zhan; Xia Ouyang; Xiaoxiang Jiang; Danlin Yang
Journal:  Arch Gynecol Obstet       Date:  2020-09-04       Impact factor: 2.344

6.  Silk-based injectable biomaterial as an alternative to cervical cerclage: an in vitro study.

Authors:  Asha J Heard; Simona Socrate; Kelly A Burke; Errol R Norwitz; David L Kaplan; Michael D House
Journal:  Reprod Sci       Date:  2012-12-27       Impact factor: 3.060

Review 7.  Preterm birth.

Authors:  David M Haas
Journal:  BMJ Clin Evid       Date:  2011-04-04

Review 8.  Vaginal progesterone vs. cervical cerclage for the prevention of preterm birth in women with a sonographic short cervix, previous preterm birth, and singleton gestation: a systematic review and indirect comparison metaanalysis.

Authors:  Agustin Conde-Agudelo; Roberto Romero; Kypros Nicolaides; Tinnakorn Chaiworapongsa; John M O'Brien; Elcin Cetingoz; Eduardo da Fonseca; George Creasy; Priya Soma-Pillay; Shalini Fusey; Cetin Cam; Zarko Alfirevic; Sonia S Hassan
Journal:  Am J Obstet Gynecol       Date:  2012-11-15       Impact factor: 8.661

9.  Periviable birth: executive summary of a Joint Workshop by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Academy of Pediatrics, and American College of Obstetricians and Gynecologists.

Authors:  T N K Raju; B M Mercer; D J Burchfield; G F Joseph
Journal:  J Perinatol       Date:  2014-04-10       Impact factor: 2.521

Review 10.  Relationships between mechanical properties and extracellular matrix constituents of the cervical stroma during pregnancy.

Authors:  Michael House; David L Kaplan; Simona Socrate
Journal:  Semin Perinatol       Date:  2009-10       Impact factor: 3.300

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