| Literature DB >> 16447157 |
Avram Z Traum1, Meghan P Wells, Manuel Aivado, Towia A Libermann, Marco F Ramoni, Asher D Schachter.
Abstract
Proteomic profiling with SELDI-TOF MS has facilitated the discovery of disease-specific protein profiles. However, multicenter studies are often hindered by the logistics required for prompt deep-freezing of samples in liquid nitrogen or dry ice within the clinic setting prior to shipping. We report high concordance between MS profiles within sets of quadruplicate split urine and serum samples deep-frozen at 0, 2, 6, and 24 h after sample collection. Gage R&R results confirm that deep-freezing times are not a statistically significant source of SELDI-TOF MS variability for either blood or urine.Entities:
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Year: 2006 PMID: 16447157 PMCID: PMC1447593 DOI: 10.1002/pmic.200500174
Source DB: PubMed Journal: Proteomics ISSN: 1615-9853 Impact factor: 3.984