Literature DB >> 1644343

Non-immunological defence mechanisms of the gut.

S A Sarker1, K Gyr.   

Abstract

Non-immunological defence mechanisms represent an important line of intestinal defence in addition to humoral and cellular immunity. This review summarises the evidence for the role of the non-immunological defence system. Protective factors that have been amply documented are gastric juice, intestinal motility, and intestinal flora. Components of pancreatic juice, lysozyme, and epithelial cell turnover may also be involved. Special attention is given to gastric acid, infection with Helicobacter pylori, and hypochlorhydria and their association with infectious diarrhoea. Epidemic hypochlorhydria is discussed since this increases sensitivity to intestinal infections in third world countries.

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Year:  1992        PMID: 1644343      PMCID: PMC1379419          DOI: 10.1136/gut.33.7.987

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  90 in total

1.  Clinical recovery owing to target parietal cell failure in a patient with Zollinger-Ellison syndrome.

Authors:  W M Wiersinga; G N Tytgat
Journal:  Gastroenterology       Date:  1977-12       Impact factor: 22.682

Review 2.  The contaminated small bowel syndrome: pathogenesis, diagnosis, and treatment.

Authors:  M Gracey
Journal:  Am J Clin Nutr       Date:  1979-01       Impact factor: 7.045

3.  Epidemic gastritis with hypochlorhydria.

Authors:  E J Ramsey; K V Carey; W L Peterson; J J Jackson; F K Murphy; N W Read; K B Taylor; J S Trier; J S Fordtran
Journal:  Gastroenterology       Date:  1979-06       Impact factor: 22.682

4.  Pathogenesis of gastric cancer in pernicious anaemia.

Authors:  W S Ruddell; E S Bone; M J Hill; C L Walters
Journal:  Lancet       Date:  1978-03-11       Impact factor: 79.321

5.  The role of IgA in the prevention of bacterial colonization of the jejunum in the vagotomized subject.

Authors:  G A McLoughlin; J E Hede; J G Temple; J Bradley; D M Chapman; J McFarland
Journal:  Br J Surg       Date:  1978-06       Impact factor: 6.939

6.  The effect of oral pancreatic enzymes on the intestinal flora of protein-deficient vervet monkeys challenged with Vibrio cholerae.

Authors:  K Gyr; O Felsenfeld; M Zimmerli-Ning
Journal:  Am J Clin Nutr       Date:  1979-08       Impact factor: 7.045

7.  Volatile fatty acids and aerobic flora in the gastrointestinal tract of mice under various conditions.

Authors:  B M Byrne; J Dankert
Journal:  Infect Immun       Date:  1979-03       Impact factor: 3.441

8.  Cholera, non-vibrio cholera, and stomach acid.

Authors:  D R Nalin; R J Levine; M M Levine; D Hoover; E Bergquist; J McLaughlin; J Libonati; J Alam; R B Hornick
Journal:  Lancet       Date:  1978-10-21       Impact factor: 79.321

9.  The effect of oral pancreatic extract on jejunal bactericidal activity in protein-deficient vervet monkeys challenged with Vibrio cholerae.

Authors:  K Gyr; O Felsenfeld
Journal:  Acta Trop       Date:  1979-06       Impact factor: 3.112

10.  Effect of oral pancreatic enzymes on the course of cholera in protein-deficient vervet monkeys.

Authors:  K Gyr; O Felsenfeld; M Zimmerli-Ning
Journal:  Gastroenterology       Date:  1978-03       Impact factor: 22.682

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  23 in total

Review 1.  Transmission of Helicobacter pylori infection.

Authors:  M A Mendall; T C Northfield
Journal:  Gut       Date:  1995-07       Impact factor: 23.059

2.  Gene expression profiling of jejunal Peyer's patches in juvenile and adult pigs.

Authors:  Juliana G Machado; Kendra A Hyland; Cheryl M T Dvorak; Michael P Murtaugh
Journal:  Mamm Genome       Date:  2005-09-14       Impact factor: 2.957

Review 3.  Acid-Suppressive Therapy and Risk of Infections: Pros and Cons.

Authors:  Leon Fisher; Alexander Fisher
Journal:  Clin Drug Investig       Date:  2017-07       Impact factor: 2.859

4.  The importance of microbiological investigations, medications and artificial feeding in diarrhoea evaluation.

Authors:  A McErlean; O Kelly; S Bergin; S E Patchett; F E Murray
Journal:  Ir J Med Sci       Date:  2005 Jan-Mar       Impact factor: 1.568

Review 5.  The production and role of gastrin-17 and gastrin-17-gly in gastrointestinal cancers.

Authors:  Jeffrey Copps; Richard F Murphy; Sándor Lovas
Journal:  Protein Pept Lett       Date:  2009       Impact factor: 1.890

6.  Mechanical bowel preparation does not affect the intramucosal bacterial colony count.

Authors:  Bärbel Jung; Peter Matthiessen; Kenneth Smedh; Erik Nilsson; Ulrika Ransjö; Lars Påhlman
Journal:  Int J Colorectal Dis       Date:  2009-12-09       Impact factor: 2.571

7.  Duodenal bacterial overgrowth during treatment in outpatients with omeprazole.

Authors:  M Fried; H Siegrist; R Frei; F Froehlich; P Duroux; J Thorens; A Blum; J Bille; J J Gonvers; K Gyr
Journal:  Gut       Date:  1994-01       Impact factor: 23.059

8.  Examination of equine glandular stomach lesions for bacteria, including Helicobacter spp by fluorescence in situ hybridisation.

Authors:  Louise Husted; Tim K Jensen; Susanne N Olsen; Lars Mølbak
Journal:  BMC Microbiol       Date:  2010-03-19       Impact factor: 3.605

9.  Small intestinal bacterial overgrowth in patients with rheumatoid arthritis.

Authors:  A E Henriksson; L Blomquist; C E Nord; T Midtvedt; A Uribe
Journal:  Ann Rheum Dis       Date:  1993-07       Impact factor: 19.103

10.  Increased accuracy of the carbon-14 D-xylose breath test in detecting small-intestinal bacterial overgrowth by correction with the gastric emptying rate.

Authors:  C S Chang; G H Chen; C H Kao; S J Wang; S N Peng; C K Huang; S K Poon
Journal:  Eur J Nucl Med       Date:  1995-10
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