BACKGROUND: The recently introduced 2004 World Health Organisation (WHO) classification of the adult renal epithelial neoplasms is meant to replace the previous 1998 WHO classification. METHODS AND RESULTS: The 2004 WHO classification is based on pathology and genetic abnormalities. The description of categories has been expanded to improve their recognition and new diagnostic categories are included. Emphasis has been placed on defining familial renal cancer, carcinoma associated with Xp11 translocations, carcinoma associated with neuroblastoma, multilocular cystic renal cell carcinoma, tubular, mucinous and spindle cells carcinoma; and mixed epithelial and stromal tumour. The potentially aggressive epithelioid angiomyolipoma is recognised. CONCLUSIONS: Recognising these categories may have important implications in patients' clinical management.
BACKGROUND: The recently introduced 2004 World Health Organisation (WHO) classification of the adult renal epithelial neoplasms is meant to replace the previous 1998 WHO classification. METHODS AND RESULTS: The 2004 WHO classification is based on pathology and genetic abnormalities. The description of categories has been expanded to improve their recognition and new diagnostic categories are included. Emphasis has been placed on defining familial renal cancer, carcinoma associated with Xp11 translocations, carcinoma associated with neuroblastoma, multilocular cystic renal cell carcinoma, tubular, mucinous and spindle cells carcinoma; and mixed epithelial and stromal tumour. The potentially aggressive epithelioid angiomyolipoma is recognised. CONCLUSIONS: Recognising these categories may have important implications in patients' clinical management.
Authors: Boyi Gan; Carol Lim; Gerald Chu; Sujun Hua; Zhihu Ding; Michael Collins; Jian Hu; Shan Jiang; Eliot Fletcher-Sananikone; Li Zhuang; Michelle Chang; Hongwu Zheng; Y Alan Wang; David J Kwiatkowski; William G Kaelin; Sabina Signoretti; Ronald A DePinho Journal: Cancer Cell Date: 2010-11-16 Impact factor: 31.743
Authors: Elzbieta Sarnowska; Michal Szymanski; Nataliia Rusetska; Marcin Ligaj; Iga Jancewicz; Pawel Cwiek; Marta Skrodzka; Marcin Leszczynski; Joanna Szarkowska; Alicja Chrzan; Malgorzata Stachowiak; Jaroslaw Steciuk; Anna Maassen; Lech Galek; Tomasz Demkow; Janusz A Siedlecki; Tomasz J Sarnowski Journal: Am J Cancer Res Date: 2017-11-01 Impact factor: 6.166
Authors: Fernando U Kay; Noah E Canvasser; Yin Xi; Daniella F Pinho; Daniel N Costa; Alberto Diaz de Leon; Gaurav Khatri; John R Leyendecker; Takeshi Yokoo; Aaron H Lay; Nicholas Kavoussi; Ersin Koseoglu; Jeffrey A Cadeddu; Ivan Pedrosa Journal: Radiology Date: 2018-02-01 Impact factor: 11.105
Authors: Aidan P Noon; Nikolina Vlatković; Radosław Polański; Maria Maguire; Howida Shawki; Keith Parsons; Mark T Boyd Journal: Cancer Date: 2010-02-15 Impact factor: 6.860