Literature DB >> 16439833

Developing a physical model of the human cochlea using micro-fabrication methods.

Michael J Wittbrodt1, Charles R Steele, Sunil Puria.   

Abstract

Advances in micro-machining technology have provided the opportunity to explore possibilities of creating life-sized physical models of the cochlea. The physical model of the cochlea consists of two fluid-filled channels separated by an elastic partition. The partition is micro-machined from silicon and uses a 36-mm linearly tapered polyimide plate with a width of 100 microm at the basal end and 500 microm at the apex to represent the basilar membrane. Thicknesses from 1 to 5 microm have been fabricated. Discrete aluminum fibers (1.5 microm in width) are machined to create direction-dependent properties. A 0.5 x 0.5 mm opening represents the helicotrema. The fluid channels are machined from plexiglas using conventional machining methods. A magnet-coil system excites the fluid channel. Measurements on a model with thickness 4.75 microm show a velocity gain of 4 and phase of 3.5 pi radians at a location 23 mm from the base. Mathematical modeling using a 3-D formulation confirm the general characteristics of the measured response.

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Year:  2006        PMID: 16439833     DOI: 10.1159/000090683

Source DB:  PubMed          Journal:  Audiol Neurootol        ISSN: 1420-3030            Impact factor:   1.854


  14 in total

1.  Piezoelectric materials mimic the function of the cochlear sensory epithelium.

Authors:  Takatoshi Inaoka; Hirofumi Shintaku; Takayuki Nakagawa; Satoyuki Kawano; Hideaki Ogita; Tatsunori Sakamoto; Shinji Hamanishi; Hiroshi Wada; Juichi Ito
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-24       Impact factor: 11.205

2.  Inertial bone conduction: symmetric and anti-symmetric components.

Authors:  Namkeun Kim; Kenji Homma; Sunil Puria
Journal:  J Assoc Res Otolaryngol       Date:  2011-03-01

Review 3.  Instrumentation for studies of cochlear mechanics: from von Békésy forward.

Authors:  Alfred L Nuttall; Anders Fridberger
Journal:  Hear Res       Date:  2012-09-10       Impact factor: 3.208

4.  A MULTISCALE MODEL OF THE ORGAN OF CORTI.

Authors:  Charles R Steele; Jacques Boutet de Monvel; Sunil Puria
Journal:  J Mech Mater Struct       Date:  2009       Impact factor: 1.210

Review 5.  Modelling cochlear mechanics.

Authors:  Guangjian Ni; Stephen J Elliott; Mohammad Ayat; Paul D Teal
Journal:  Biomed Res Int       Date:  2014-07-23       Impact factor: 3.411

6.  A three-dimensional finite element model of round window membrane vibration before and after stapedotomy surgery.

Authors:  Monika Kwacz; Piotr Marek; Paweł Borkowski; Maciej Mrówka
Journal:  Biomech Model Mechanobiol       Date:  2013-03-05

7.  A microelectromechanical system artificial basilar membrane based on a piezoelectric cantilever array and its characterization using an animal model.

Authors:  Jongmoon Jang; JangWoo Lee; Seongyong Woo; David J Sly; Luke J Campbell; Jin-Ho Cho; Stephen J O'Leary; Min-Hyun Park; Sungmin Han; Ji-Wong Choi; Jeong Hun Jang; Hongsoo Choi
Journal:  Sci Rep       Date:  2015-07-31       Impact factor: 4.379

8.  Mechanical and Electrical Characterization of Piezoelectric Artificial Cochlear Device and Biocompatible Packaging.

Authors:  Youngdo Jung; Jun-Hyuk Kwak; Hanmi Kang; Wan Doo Kim; Shin Hur
Journal:  Sensors (Basel)       Date:  2015-07-31       Impact factor: 3.576

9.  Development of a multi-channel piezoelectric acoustic sensor based on an artificial basilar membrane.

Authors:  Youngdo Jung; Jun-Hyuk Kwak; Young Hwa Lee; Wan Doo Kim; Shin Hur
Journal:  Sensors (Basel)       Date:  2013-12-20       Impact factor: 3.576

Review 10.  Toward a neuromorphic microphone.

Authors:  Leslie S Smith
Journal:  Front Neurosci       Date:  2015-10-26       Impact factor: 4.677

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