| Literature DB >> 16438051 |
Didier Gasparutto1, Sonia Cognet, Solveig Roussel, Jean Cadet.
Abstract
An original phosphoramidite building block of the thymidine glycol lesion has been prepared taking into account the additional diol function and the high lability of this oxidatively induced nucleobase damage. Then the modified nucleoside was site-specifically inserted into DNA fragments by solid support assembling followed by a "one-step" mild final deprotection treatment.Entities:
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Year: 2005 PMID： 16438051 DOI： 10.1080/15257770500267279
Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN： 1525-7770 Impact factor: 1.381