Literature DB >> 16436743

Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection.

Marie-Eve Hamelin1, Gregory A Prince, Guy Boivin.   

Abstract

Human metapneumovirus (hMPV)-infected BALB/c mice were treated with ribavirin (40 mg/kg of body weight twice a day intraperitoneally), corticosterone (0.2 mg/ml in water), or both modalities. Ribavirin significantly decreased both hMPV replication in lungs (by 5 log10) and global pulmonary inflammation on day 5 postinfection, whereas glucocorticoids reduced only alveolar and interstitial inflammation, compared to controls.

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Year:  2006        PMID： 16436743      PMCID： PMC1366914          DOI： 10.1128/AAC.50.2.774-777.2006

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

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2.  Pulmonary lesions in primary respiratory syncytial virus infection, reinfection, and vaccine-enhanced disease in the cotton rat (Sigmodon hispidus).

Authors:  G A Prince; J P Prieels; M Slaoui; D D Porter
Journal:  Lab Invest       Date:  1999-11       Impact factor: 5.662

3.  In vivo inhibition of respiratory syncytial virus by ribavirin.

Authors:  J F Hruska; P E Morrow; S C Suffin; R G Douglas
Journal:  Antimicrob Agents Chemother       Date:  1982-01       Impact factor: 5.191

4.  Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitro.

Authors:  Philip R Wyde; Srikrishna N Chetty; Alan M Jewell; Guy Boivin; Pedro A Piedra
Journal:  Antiviral Res       Date:  2003-09       Impact factor: 5.970

5.  The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity.

Authors:  John V Williams; Sharon J Tollefson; Joyce E Johnson; James E Crowe
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

6.  Early ribavarin treatment of bronchiolitis: effect on long-term respiratory morbidity.

Authors:  Dean Edell; Vikram Khoshoo; Gerald Ross; Karen Salter
Journal:  Chest       Date:  2002-09       Impact factor: 9.410

7.  Respiratory syncytial virus induces pneumonia, cytokine response, airway obstruction, and chronic inflammatory infiltrates associated with long-term airway hyperresponsiveness in mice.

Authors:  Hasan S Jafri; Susana Chavez-Bueno; Asuncion Mejias; Ana M Gomez; Ana M Rios; Shahryar S Nassi; Munira Yusuf; Payal Kapur; Robert D Hardy; Jeanine Hatfield; Beverly B Rogers; Karen Krisher; Octavio Ramilo
Journal:  J Infect Dis       Date:  2004-04-29       Impact factor: 5.226

8.  Identification of small-animal and primate models for evaluation of vaccine candidates for human metapneumovirus (hMPV) and implications for hMPV vaccine design.

Authors:  Mia MacPhail; Jeanne H Schickli; Roderick S Tang; Jasmine Kaur; Christopher Robinson; Ron A M Fouchier; Albert D M E Osterhaus; Richard R Spaete; Aurelia A Haller
Journal:  J Gen Virol       Date:  2004-06       Impact factor: 3.891

9.  A newly discovered human pneumovirus isolated from young children with respiratory tract disease.

Authors:  B G van den Hoogen; J C de Jong; J Groen; T Kuiken; R de Groot; R A Fouchier; A D Osterhaus
Journal:  Nat Med       Date:  2001-06       Impact factor: 53.440

10.  Human metapneumovirus: a new player among respiratory viruses.

Authors:  Marie-Eve Hamelin; Yacine Abed; Guy Boivin
Journal:  Clin Infect Dis       Date:  2004-03-15       Impact factor: 9.079
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  34 in total

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Journal:  Transpl Infect Dis       Date:  2010-10-03       Impact factor: 2.228

2.  Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective.

Authors:  Marcie Tomblyn; Tom Chiller; Hermann Einsele; Ronald Gress; Kent Sepkowitz; Jan Storek; John R Wingard; Jo-Anne H Young; Michael J Boeckh; Michael A Boeckh
Journal:  Biol Blood Marrow Transplant       Date:  2009-10       Impact factor: 5.742

Review 3.  New Approaches for Immunization and Therapy against Human Metapneumovirus.

Authors:  Sherry C Wen; John V Williams
Journal:  Clin Vaccine Immunol       Date:  2015-06-10

Review 4.  How I treat respiratory viral infections in the setting of intensive chemotherapy or hematopoietic cell transplantation.

Authors:  Alpana Waghmare; Janet A Englund; Michael Boeckh
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5.  Management of respiratory viral infections in hematopoietic cell transplant recipients.

Authors:  Dimpy P Shah; Shashank S Ghantoji; Victor E Mulanovich; Ella J Ariza-Heredia; Roy F Chemaly
Journal:  Am J Blood Res       Date:  2012-11-25

6.  Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirus.

Authors:  Céline Deffrasnes; Marie-Eve Hamelin; Gregory A Prince; Guy Boivin
Journal:  Antimicrob Agents Chemother       Date:  2007-10-29       Impact factor: 5.191

Review 7.  Respiratory viruses other than influenza virus: impact and therapeutic advances.

Authors:  W Garrett Nichols; Angela J Peck Campbell; Michael Boeckh
Journal:  Clin Microbiol Rev       Date:  2008-04       Impact factor: 26.132

8.  Airway epithelial cell response to human metapneumovirus infection.

Authors:  X Bao; T Liu; L Spetch; D Kolli; R P Garofalo; A Casola
Journal:  Virology       Date:  2007-07-25       Impact factor: 3.616

Review 9.  Human metapneumovirus infections in hematopoietic cell transplant recipients and hematologic malignancy patients: A systematic review.

Authors:  Dimpy P Shah; Pankil K Shah; Jacques M Azzi; Firas El Chaer; Roy F Chemaly
Journal:  Cancer Lett       Date:  2016-05-31       Impact factor: 8.679

10.  Effect of NMSO3 treatment in a murine model of human metapneumovirus infection.

Authors:  Leanne Spetch; Terry L Bowlin; Antonella Casola
Journal:  J Gen Virol       Date:  2008-11       Impact factor: 3.891
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