| Literature DB >> 16436741 |
Klaudia Kosowska-Shick1, Catherine Clark, Kim Credito, Pamela McGhee, Bonifacio Dewasse, Tatiana Bogdanovich, Peter C Appelbaum.
Abstract
Retapamulin had the lowest rate of spontaneous mutations by single-step passaging and the lowest parent and selected mutant MICs by multistep passaging among all drugs tested for all Staphylococcus aureus strains and three Streptococcus pyogenes strains which yielded resistant clones. Retapamulin has a low potential for resistance selection in S. pyogenes, with a slow and gradual propensity for resistance development in S. aureus.Entities:
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Year: 2006 PMID: 16436741 PMCID: PMC1366917 DOI: 10.1128/AAC.50.2.765-769.2006
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191