Literature DB >> 16436735

Inhibition of Candida parapsilosis mitochondrial respiratory pathways enhances susceptibility to caspofungin.

Georgios Chamilos1, Russell E Lewis, Dimitrios P Kontoyiannis.   

Abstract

Among the Candida species, Candida parapsilosis has a unique mitochondrial respiratory network. The addition of inhibitors of the respiratory pathways in three clinical isolates of C. parapsilosis with high (> or =2- microg/ml) MICs of caspofungin significantly (fivefold) decreased caspofungin MICs but did not change fluconazole MICs.

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Year:  2006        PMID： 16436735      PMCID： PMC1366909          DOI： 10.1128/AAC.50.2.744-747.2006

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Respiratory chain network in mitochondria of Candida parapsilosis: ADP/O appraisal of the multiple electron pathways.

Authors:  G Milani; W Jarmuszkiewicz; C M Sluse-Goffart; A Z Schreiber; A E Vercesi; F E Sluse
Journal:  FEBS Lett       Date:  2001-11-16       Impact factor: 4.124

2.  Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species.

Authors:  Frank C Odds; Mary Motyl; Roberto Andrade; Jacques Bille; Emilia Cantón; Manuel Cuenca-Estrella; Amanda Davidson; Christian Durussel; David Ellis; Elyse Foraker; Annette W Fothergill; Mahmoud A Ghannoum; Robert A Giacobbe; Miguel Gobernado; Rosemary Handke; Michel Laverdière; Wendy Lee-Yang; William G Merz; Luis Ostrosky-Zeichner; Javier Pemán; Sophia Perea; John R Perfect; Michael A Pfaller; Laurie Proia; John H Rex; Michael G Rinaldi; Juan-Luis Rodriguez-Tudela; Wiley A Schell; Christine Shields; Deanna A Sutton; Paul E Verweij; David W Warnock
Journal:  J Clin Microbiol       Date:  2004-08       Impact factor: 5.948

3.  Trends in antifungal susceptibility of Candida spp. isolated from pediatric and adult patients with bloodstream infections: SENTRY Antimicrobial Surveillance Program, 1997 to 2000.

Authors:  M A Pfaller; D J Diekema; R N Jones; S A Messer; R J Hollis
Journal:  J Clin Microbiol       Date:  2002-03       Impact factor: 5.948

4.  Resistance of Candida parapsilosis to drugs.

Authors:  N Camougrand; G Velours; M Guerin
Journal:  Biol Cell       Date:  1986       Impact factor: 4.458

5.  Colorimetric assay for antifungal susceptibility testing of Aspergillus species.

Authors:  J Meletiadis; J W Mouton; J F Meis; B A Bouman; J P Donnelly; P E Verweij
Journal:  J Clin Microbiol       Date:  2001-09       Impact factor: 5.948

6.  Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies.

Authors:  M B Kurtz; G Abruzzo; A Flattery; K Bartizal; J A Marrinan; W Li; J Milligan; K Nollstadt; C M Douglas
Journal:  Infect Immun       Date:  1996-08       Impact factor: 3.441

7.  Multiechinocandin- and multiazole-resistant Candida parapsilosis isolates serially obtained during therapy for prosthetic valve endocarditis.

Authors:  Varsha Moudgal; Tania Little; Dina Boikov; Jose A Vazquez
Journal:  Antimicrob Agents Chemother       Date:  2005-02       Impact factor: 5.191

8.  Caspofungin.

Authors:  Stanley C Deresinski; David A Stevens
Journal:  Clin Infect Dis       Date:  2003-05-19       Impact factor: 9.079

Review 9.  Candida infections in the neonate.

Authors:  Rachel L Chapman
Journal:  Curr Opin Pediatr       Date:  2003-02       Impact factor: 2.856

10.  Caspofungin resistance in Candida albicans: correlating clinical outcome with laboratory susceptibility testing of three isogenic isolates serially obtained from a patient with progressive Candida esophagitis.

Authors:  Steve Hernandez; José L López-Ribot; Laura K Najvar; Dora I McCarthy; Rosie Bocanegra; John R Graybill
Journal:  Antimicrob Agents Chemother       Date:  2004-04       Impact factor: 5.191
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  21 in total

1.  Mitochondrial sorting and assembly machinery subunit Sam37 in Candida albicans: insight into the roles of mitochondria in fitness, cell wall integrity, and virulence.

Authors:  Yue Qu; Branka Jelicic; Filomena Pettolino; Andrew Perry; Tricia L Lo; Victoria L Hewitt; Farkad Bantun; Traude H Beilharz; Anton Y Peleg; Trevor Lithgow; Julianne T Djordjevic; Ana Traven
Journal:  Eukaryot Cell       Date:  2012-01-27

2.  Novel FKS mutations associated with echinocandin resistance in Candida species.

Authors:  Guillermo Garcia-Effron; Daniel Joseph Chua; Jon Rupert Tomada; Joseph DiPersio; David S Perlin; Mahmoud Ghannoum; Hector Bonilla
Journal:  Antimicrob Agents Chemother       Date:  2010-02-09       Impact factor: 5.191

Review 3.  Mitochondria and fungal pathogenesis: drug tolerance, virulence, and potential for antifungal therapy.

Authors:  Miguel Shingu-Vazquez; Ana Traven
Journal:  Eukaryot Cell       Date:  2011-09-16

4.  Nutrient-Dependent Efficacy of the Antifungal Protein YvgO Correlates to Cellular Proliferation Rate in Candida albicans 3153A and Byssochlamys fulva H25.

Authors:  David C Manns; John J Churey; Randy W Worobo
Journal:  Probiotics Antimicrob Proteins       Date:  2014-12       Impact factor: 4.609

Review 5.  Candida parapsilosis: from Genes to the Bedside.

Authors:  Renáta Tóth; Jozef Nosek; Héctor M Mora-Montes; Toni Gabaldon; Joseph M Bliss; Joshua D Nosanchuk; Siobhán A Turner; Geraldine Butler; Csaba Vágvölgyi; Attila Gácser
Journal:  Clin Microbiol Rev       Date:  2019-02-27       Impact factor: 26.132

6.  Amino acid-derived 1,2-benzisothiazolinone derivatives as novel small-molecule antifungal inhibitors: identification of potential genetic targets.

Authors:  Deepu Alex; Francoise Gay-Andrieu; Jared May; Linta Thampi; Dengfeng Dou; Aileen Mooney; William Groutas; Richard Calderone
Journal:  Antimicrob Agents Chemother       Date:  2012-06-11       Impact factor: 5.191

Review 7.  Biology and genetics of the pathogenic yeast Candida parapsilosis.

Authors:  Jozef Nosek; Zuzana Holesova; Peter Kosa; Attila Gacser; Lubomir Tomaska
Journal:  Curr Genet       Date:  2009-08-07       Impact factor: 3.886

8.  Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin.

Authors:  Jarrod R Fortwendel; Praveen R Juvvadi; B Zachary Perfect; Luise E Rogg; John R Perfect; William J Steinbach
Journal:  Antimicrob Agents Chemother       Date:  2010-02-01       Impact factor: 5.191

9.  Link between Heat Shock Protein 90 and the Mitochondrial Respiratory Chain in the Caspofungin Stress Response of Aspergillus fumigatus.

Authors:  M Aruanno; D Bachmann; D Sanglard; F Lamoth
Journal:  Antimicrob Agents Chemother       Date:  2019-06-24       Impact factor: 5.191

10.  Anidulafungin versus caspofungin in a mouse model of candidiasis caused by anidulafungin-susceptible Candida parapsilosis isolates with different degrees of caspofungin susceptibility.

Authors:  Dimitra Dimopoulou; Georgios Hamilos; Maria Tzardi; Russell E Lewis; George Samonis; Dimitrios P Kontoyiannis
Journal:  Antimicrob Agents Chemother       Date:  2013-10-21       Impact factor: 5.191
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