AIMS: (1) To confirm that head-up tilting causes sustained increases in the heart rate (HR) of newborn infants but not during the period of maximum vulnerability to SIDS at 2-4 mo of age, and (2) to determine whether electrocortical activation (changes in high-frequency EEG power) also shows topographic and age-dependent effects of tilting. METHODS: HR and electrocortical activity were recorded in 15 newborn and 12 2- to 4-mo-old infants during head-up tilting. Infants were tilted, three times, to a 30 degrees head-up position. Electrocortical activity was acquired using a 128-lead EEG system. Changes in HR and high-frequency (12-50 Hz) power in the electrocortical signal were computed from the flat to the head-up position. RESULTS: Newborn infants had significant increases in HR and robust increases in high-frequency power in the left frontal, right frontal-temporal, and occipital regions following head-up tilt. At 2 to 4 mo of age, HR did not change significantly and tilt-related increases in high-frequency power were smaller. CONCLUSION: The patterns of HR change and electrocortical activation with tilting of newborn infants are different from infants at the age of highest risk for SIDS.
AIMS: (1) To confirm that head-up tilting causes sustained increases in the heart rate (HR) of newborn infants but not during the period of maximum vulnerability to SIDS at 2-4 mo of age, and (2) to determine whether electrocortical activation (changes in high-frequency EEG power) also shows topographic and age-dependent effects of tilting. METHODS: HR and electrocortical activity were recorded in 15 newborn and 12 2- to 4-mo-old infants during head-up tilting. Infants were tilted, three times, to a 30 degrees head-up position. Electrocortical activity was acquired using a 128-lead EEG system. Changes in HR and high-frequency (12-50 Hz) power in the electrocortical signal were computed from the flat to the head-up position. RESULTS: Newborn infants had significant increases in HR and robust increases in high-frequency power in the left frontal, right frontal-temporal, and occipital regions following head-up tilt. At 2 to 4 mo of age, HR did not change significantly and tilt-related increases in high-frequency power were smaller. CONCLUSION: The patterns of HR change and electrocortical activation with tilting of newborn infants are different from infants at the age of highest risk for SIDS.
Authors: Philip G Grieve; Joseph R Isler; Asya Izraelit; Bradley S Peterson; William P Fifer; Michael M Myers; Raymond I Stark Journal: Clin Neurophysiol Date: 2008-11-04 Impact factor: 3.708