Literature DB >> 16418868

Pipecolic acid in microbes: biosynthetic routes and enzymes.

Min He1.   

Abstract

Pipecolic acid is an important precursor of many useful microbial secondary metabolites. Pipecolic acid-derived moieties are often crucial for the biological activities of some microbial natural products with pharmaceutical applications. Understanding the biogenesis of pipecolic acid in microorganisms would be a significant step toward the mutasynthesis of novel analogs of choice. This review focuses on various microbial pathways and enzymes for pipecolic acid synthesis, especially those related to the origination of pipecolic acid moieties in secondary metabolites.

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Year:  2006        PMID: 16418868     DOI: 10.1007/s10295-006-0078-3

Source DB:  PubMed          Journal:  J Ind Microbiol Biotechnol        ISSN: 1367-5435            Impact factor:   3.346


  46 in total

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Journal:  Science       Date:  1996-07-12       Impact factor: 47.728

6.  The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.

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Journal:  Gene       Date:  2000-06-13       Impact factor: 3.688

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Journal:  J Bacteriol       Date:  1974-02       Impact factor: 3.490

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Journal:  J Gen Microbiol       Date:  1977-03

9.  Inactivation of the lys7 gene, encoding saccharopine reductase in Penicillium chrysogenum, leads to accumulation of the secondary metabolite precursors piperideine-6-carboxylic acid and pipecolic acid from alpha-aminoadipic acid.

Authors:  Leopoldo Naranjo; Eva Martín de Valmaseda; Javier Casqueiro; Ricardo V Ullán; Mónica Lamas-Maceiras; Oscar Bañuelos; Juan F Martín
Journal:  Appl Environ Microbiol       Date:  2004-02       Impact factor: 4.792

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Journal:  J Bacteriol       Date:  1998-02       Impact factor: 3.490

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  17 in total

1.  Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster.

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Journal:  J Biol Chem       Date:  2010-08-14       Impact factor: 5.157

Review 2.  Expanding lysine industry: industrial biomanufacturing of lysine and its derivatives.

Authors:  Jie Cheng; Peng Chen; Andong Song; Dan Wang; Qinhong Wang
Journal:  J Ind Microbiol Biotechnol       Date:  2018-04-13       Impact factor: 3.346

3.  An economically and environmentally acceptable synthesis of chiral drug intermediate L-pipecolic acid from biomass-derived lysine via artificially engineered microbes.

Authors:  Jie Cheng; Yuding Huang; Le Mi; Wujiu Chen; Dan Wang; Qinhong Wang
Journal:  J Ind Microbiol Biotechnol       Date:  2018-05-10       Impact factor: 3.346

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Journal:  J Cell Sci       Date:  2015-01-22       Impact factor: 5.285

6.  Variation in Root Exudate Composition Influences Soil Microbiome Membership and Function.

Authors:  Valerie A Seitz; Bridget B McGivern; Rebecca A Daly; Jacqueline M Chaparro; Mikayla A Borton; Amy M Sheflin; Stephen Kresovich; Lindsay Shields; Meagan E Schipanski; Kelly C Wrighton; Jessica E Prenni
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7.  Almond Consumption for 8 Weeks Altered Host and Microbial Metabolism in Comparison to a Control Snack in Young Adults.

Authors:  Jaapna Dhillon; John W Newman; Oliver Fiehn; Rudy M Ortiz
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8.  Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies.

Authors:  Thushanthi Perera; Matthew R Young; Zhiying Zhang; Gwen Murphy; Nancy H Colburn; Elaine Lanza; Terryl J Hartman; Amanda J Cross; Gerd Bobe
Journal:  Mol Nutr Food Res       Date:  2015-02-23       Impact factor: 5.914

9.  Novel Enzyme Family Found in Filamentous Fungi Catalyzing trans-4-Hydroxylation of L-Pipecolic Acid.

Authors:  Makoto Hibi; Ryosuke Mori; Ryoma Miyake; Hiroshi Kawabata; Shoko Kozono; Satomi Takahashi; Jun Ogawa
Journal:  Appl Environ Microbiol       Date:  2016-01-22       Impact factor: 4.792

10.  Plasma and Urine Metabolite Profiles Impacted by Increased Dietary Navy Bean Intake in Colorectal Cancer Survivors: A Randomized-Controlled Trial.

Authors:  Iman Zarei; Bridget A Baxter; Renee C Oppel; Erica C Borresen; Regina J Brown; Elizabeth P Ryan
Journal:  Cancer Prev Res (Phila)       Date:  2020-12-24
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