Literature DB >> 16417664

Drooling in children with cerebral palsy: effect of salivary flow reduction on daily life and care.

Jan J W Van der Burg1, Peter H Jongerius, Karen Van Hulst, Jacques Van Limbeek, Jan J Rotteveel.   

Abstract

The purpose of this study was to investigate the effect of salivary flow reduction on daily life and provision of care in children with cerebral palsy (CP). Parents of children with CP were asked to fill in a questionnaire on the impact of drooling on the daily life of their children and their families and the data were then analyzed. Forty-five children with severe drooling (28 males, 17 females; mean age 9y 5mo [SD 3y 7mo]; range 3 to 16y) were monitored before and after receiving medication (scopolamine and botulinum toxin) to reduce salivary flow. Type of CP included hypotonia (n = 1), spastic paresis (n = 27), and mixed motor disorders with spastic and dyskinetic paresis (n = 17). Eight children were independently ambulant and 37 children were wheelchair users. Thirty-four children had learning disability with a developmental age of below 6 years. Six participants dropped out of the study; data on 39 children were analyzed. Results showed that anticholinergic agents effectively reduced salivary flow. Drooling diminished substantially and this was accompanied by a significant reduction in care needs, making daily care less demanding. The amount of reported damage to communication devices and computers decreased. In addition to the evaluation of primary variables, such as the salivary flow rate, investigation of impact of drooling on daily life provides useful information about the outcome of treatment for reduction in drooling.

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Year:  2006        PMID: 16417664     DOI: 10.1017/S0012162206000235

Source DB:  PubMed          Journal:  Dev Med Child Neurol        ISSN: 0012-1622            Impact factor:   5.449


  12 in total

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2.  Randomized Phase III evaluation of the efficacy and safety of a novel glycopyrrolate oral solution for the management of chronic severe drooling in children with cerebral palsy or other neurologic conditions.

Authors:  Robert S Zeller; Hak-Myung Lee; Paul F Cavanaugh; Jennifer Davidson
Journal:  Ther Clin Risk Manag       Date:  2012-01-25       Impact factor: 2.423

3.  Impact of oral health behaviors on dental caries in children with intellectual disabilities in Guangzhou, China.

Authors:  Zifeng Liu; Dongsheng Yu; Wei Luo; Jing Yang; Jiaxuan Lu; Shuo Gao; Wenqing Li; Wei Zhao
Journal:  Int J Environ Res Public Health       Date:  2014-10-22       Impact factor: 3.390

4.  Changes in severity and impact of drooling after submandibular gland botulinum neurotoxin A injections in children with neurodevelopmental disabilities.

Authors:  Karen Van Hulst; Jan Jw Van Der Burg; Peter H Jongerius; Alexander Ch Geurts; Corrie E Erasmus
Journal:  Dev Med Child Neurol       Date:  2019-11-14       Impact factor: 5.449

5.  Cost-effectiveness of botulinum neurotoxin A versus surgery for drooling: a randomized clinical trial.

Authors:  Stijn Bekkers; Kim J van Ulsen; Eddy M M Adang; Arthur R T Scheffer; Frank J A van den Hoogen
Journal:  Dev Med Child Neurol       Date:  2020-07-24       Impact factor: 5.449

6.  Efficacy of scopolamine transdermal patch in children with sialorrhea in a pediatric tertiary care hospital.

Authors:  Majed Al Jeraisy; Maissa AlFuraih; Raghad AlSaif; Bushra AlKhalifah; Hazza AlOtaibi; Mostafa A Abolfotouh
Journal:  BMC Pediatr       Date:  2020-09-17       Impact factor: 2.125

7.  The association of drooling and health-related quality of life in children with cerebral palsy.

Authors:  Shih-Chung Chang; Chin-Kai Lin; Li-Chen Tung; Nai-Yin Chang
Journal:  Neuropsychiatr Dis Treat       Date:  2012-12-11       Impact factor: 2.570

8.  The drooling reduction intervention trial (DRI): a single blind trial comparing the efficacy of glycopyrronium and hyoscine on drooling in children with neurodisability.

Authors:  Jeremy R Parr; Emma Weldon; Lindsay Pennington; Nick Steen; Jane Williams; Charlie Fairhurst; Anne O'Hare; Raj Lodh; Allan Colver
Journal:  Trials       Date:  2014-02-17       Impact factor: 2.279

9.  Drooling Reduction Intervention randomised trial (DRI): comparing the efficacy and acceptability of hyoscine patches and glycopyrronium liquid on drooling in children with neurodisability.

Authors:  Jeremy R Parr; Emma Todhunter; Lindsay Pennington; Deborah Stocken; Jill Cadwgan; Anne E O'Hare; Catherine Tuffrey; Jane Williams; Mike Cole; Allan F Colver
Journal:  Arch Dis Child       Date:  2017-11-30       Impact factor: 3.791

10.  Salivary gland ablation: introducing an interventional radiology treatment alternative in the management of sialorrhea.

Authors:  Katherine A Begley; Leah E Braswell; Garey H Noritz; James W Murakami
Journal:  Pediatr Radiol       Date:  2020-03-21
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