Literature DB >> 16401855

Patterns of atrophy in pathologically confirmed FTLD with and without motor neuron degeneration.

Jennifer L Whitwell1, Clifford R Jack, Matthew L Senjem, Keith A Josephs.   

Abstract

The authors used voxel-based morphometry to compare the patterns of brain atrophy in two variants of pathologically confirmed frontotemporal lobar degeneration (FTLD): FTLD with motor neuron disease (FTLD-MND) and FTLD with ubiquitin-only-immunoreactive neuronal changes (FTLD-U). Patterns of atrophy were distinct and different from each other. A localized pattern of frontal lobe atrophy was found in FTLD-MND with a more widespread pattern of atrophy affecting the frontal and temporal lobes in FTLD-U.

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Year:  2006        PMID： 16401855      PMCID： PMC2752419          DOI： 10.1212/01.wnl.0000191395.69438.12

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  9 in total

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  9 in total
  36 in total

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