OBJECTIVE: To improve clinical recognition and provide research diagnostic criteria for three clinical syndromes associated with frontotemporal lobar degeneration. METHODS: Consensus criteria for the three prototypic syndromes-frontotemporal dementia, progressive nonfluent aphasia, and semantic dementia-were developed by members of an international workshop on frontotemporal lobar degeneration. These criteria build on earlier published clinical diagnostic guidelines for frontotemporal dementia produced by some of the workshop members. RESULTS: The consensus criteria specify core and supportive features for each of the three prototypic clinical syndromes and provide broad inclusion and exclusion criteria for the generic entity of frontotemporal lobar degeneration. The criteria are presented in lists, and operational definitions for features are provided in the text. CONCLUSIONS: The criteria ought to provide the foundation for research work into the neuropsychology, neuropathology, genetics, molecular biology, and epidemiology of these important clinical disorders that account for a substantial proportion of cases of primary degenerative dementia occurring before the age of 65 years.
OBJECTIVE: To improve clinical recognition and provide research diagnostic criteria for three clinical syndromes associated with frontotemporal lobar degeneration. METHODS: Consensus criteria for the three prototypic syndromes-frontotemporal dementia, progressive nonfluent aphasia, and semantic dementia-were developed by members of an international workshop on frontotemporal lobar degeneration. These criteria build on earlier published clinical diagnostic guidelines for frontotemporal dementia produced by some of the workshop members. RESULTS: The consensus criteria specify core and supportive features for each of the three prototypic clinical syndromes and provide broad inclusion and exclusion criteria for the generic entity of frontotemporal lobar degeneration. The criteria are presented in lists, and operational definitions for features are provided in the text. CONCLUSIONS: The criteria ought to provide the foundation for research work into the neuropsychology, neuropathology, genetics, molecular biology, and epidemiology of these important clinical disorders that account for a substantial proportion of cases of primary degenerative dementia occurring before the age of 65 years.
Authors: Keith A Josephs; Melissa E Murray; Nirubol Tosakulwong; Stephen D Weigand; Amanda M Serie; Ralph B Perkerson; Billie J Matchett; Clifford R Jack; David S Knopman; Ronald C Petersen; Joseph E Parisi; Leonard Petrucelli; Matthew Baker; Rosa Rademakers; Jennifer L Whitwell; Dennis W Dickson Journal: Acta Neuropathol Date: 2019-01-02 Impact factor: 17.088
Authors: Linda L Chao; Norbert Schuff; Erin M Clevenger; Susanne G Mueller; Howard J Rosen; Maria L Gorno-Tempini; Joel H Kramer; Bruce L Miller; Michael W Weiner Journal: Arch Neurol Date: 2007-11
Authors: Teresa Q Wu; Zachary A Miller; Babu Adhimoolam; Diana D Zackey; Baber K Khan; Robin Ketelle; Katherine P Rankin; Bruce L Miller Journal: Neurocase Date: 2013-12-12 Impact factor: 0.881
Authors: Agustín Ruiz; Isabel Hernández; Maiteé Ronsende-Roca; Antonio González-Pérez; Emma Rodriguez-Noriega; Reposo Ramírez-Lorca; Ana Mauleón; Concha Moreno-Rey; Lucie Boswell; Larry Tune; Sergi Valero; Montserrat Alegret; Javier Gayán; James T Becker; Luis Miguel Real; Lluís Tárraga; Clive Ballard; Michael Terrin; Stephanie Sherman; Haydeh Payami; Oscar L López; Jacobo E Mintzer; Mercè Boada Journal: Neurobiol Aging Date: 2012-10-01 Impact factor: 4.673