Literature DB >> 16397850

Antidiarrhoeal evaluation of Aegle Marmelos (Correa) Linn. root extract.

R Mazumder1, S Bhattacharya, Avijit Mazumder, A K Pattnaik, P M Tiwary, S Chaudhary.   

Abstract

A study was undertaken to evaluate the in vitro and in vivo antidiarrhoeal potential of chloroform extract of the root of Aegle marmelos (Correa) Linn. The in vitro activity was determined by agar dilution and disc diffusion techniques. The extract was studied in vivo in rats. Of the 35 tested pathogenic diarrhoea causing strains, the extract was found to be mostly active against the strains of Vibrio cholerae, followed by Escherichia coli and Shigella spp. The in vitro activity was found to be comparable to that of ciprofloxacin. Further, Aegle marmelos root extract (AMRE) treated animals showed significant inhibitory activity against castor oil-induced diarrhoea. The results so obtained thus established the efficacy of AMRE as an effective antidiarrhoeal agent. Copyright 2006 John Wiley & Sons, Ltd.

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Year:  2006        PMID： 16397850     DOI： 10.1002/ptr.1804

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  10 in total

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