Literature DB >> 16394533

Inhibition of Helicobacter pylori motility by (+)-Syringaresinol from unripe Japanese apricot.

Mitsuo Miyazawa1, Hirotoshi Utsunomiya, Ken-Ichi Inada, Tomoki Yamada, Yoshiharu Okuno, Harunari Tanaka, Masae Tatematsu.   

Abstract

A methanol extract from unripe Japanese apricot showed inhibitory activity of Helicobacter pylori motility. Inhibitory compound 1 was isolated and identified as (+)-syringaresinol (1) by spectoroscopic means. (+)-Syringaresinol (1) inhibited >90% of the H. pylori motility at a concentration of 500 microg/ml and the IC50 value was 50 microg/ml.

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Year:  2006        PMID： 16394533     DOI： 10.1248/bpb.29.172

Source DB:  PubMed          Journal:  Biol Pharm Bull        ISSN： 0918-6158            Impact factor:   2.233


  10 in total

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  10 in total

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