Literature DB >> 1639412

A cluster of expressed zinc finger protein genes in the pericentromeric region of human chromosome 10.

M F Rousseau-Merck1, A Tunnacliffe, R Berger, B A Ponder, H J Thiesen.   

Abstract

Three members of the human zinc finger Krüppel family, ZNF11/KOX2, ZNF22/KOX15, and ZNF25/KOX19, have been regionally localized to the pericentromeric region of chromosome 10 by in situ chromosomal hybridization and somatic cell hybrid analysis. ZNF25/KOX19 is located centromeric to a breakpoint in chromosome band 10q11.2 in the chromosome region 10p11.2-q11.2, whereas ZNF22/KOX15 maps distal to it in band 10q11.2. Sequences hybridizing to the KOX2 probe are found at two loci, ZNF11A and ZNF11B, that map proximal and distal to the 10q11.2 breakpoint, respectively. The two ZNF11 loci probably represent two related sequences in 10p11.2-q11.2. This cluster of ZNF/KOX genes is of particular interest since the loci for multiple endocrine neoplasia type 2A and 2B (MEN2A and MEN2B) syndromes have been assigned to this region by linkage analysis.

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Year:  1992        PMID: 1639412     DOI: 10.1016/0888-7543(92)90166-p

Source DB:  PubMed          Journal:  Genomics        ISSN: 0888-7543            Impact factor:   5.736


  11 in total

1.  The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues.

Authors:  Peter Lorenz; Sabine Dietmann; Thomas Wilhelm; Dirk Koczan; Sandra Autran; Sophie Gad; Gaiping Wen; Guohui Ding; Yixue Li; Marie-Françoise Rousseau-Merck; Hans-Juergen Thiesen
Journal:  BMC Genomics       Date:  2010-03-26       Impact factor: 3.969

2.  Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

Authors:  E J Bellefroid; J C Marine; A G Matera; C Bourguignon; T Desai; K C Healy; P Bray-Ward; J A Martial; J N Ihle; D C Ward
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-07       Impact factor: 11.205

3.  Construction of radiation-reduced hybrids and their use in mapping of microclones from chromosome 10p11.2-q11.2.

Authors:  S Fujita; E Shin; T Nakamura; H Kurahashi; Y Kaneda; K Tanaka; T Mori; S Takai; I Nishisho
Journal:  Jpn J Hum Genet       Date:  1993-12

4.  A multiple interval physical map of the pericentromeric region of human chromosome 10.

Authors:  A Tunnacliffe; M S Jackson; E Gardner; D R Love; J K Moore; S E Mole; L M Mulligan; A Graham; G Finocchiaro; S Orstavik
Journal:  Hum Genet       Date:  1994-03       Impact factor: 4.132

5.  A comprehensive catalog of human KRAB-associated zinc finger genes: insights into the evolutionary history of a large family of transcriptional repressors.

Authors:  Stuart Huntley; Daniel M Baggott; Aaron T Hamilton; Mary Tran-Gyamfi; Shan Yang; Joomyeong Kim; Laurie Gordon; Elbert Branscomb; Lisa Stubbs
Journal:  Genome Res       Date:  2006-04-10       Impact factor: 9.043

6.  Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution.

Authors:  A Tunnacliffe; L Liu; J K Moore; M A Leversha; M S Jackson; L Papi; M A Ferguson-Smith; H J Thiesen; B A Ponder
Journal:  Nucleic Acids Res       Date:  1993-03-25       Impact factor: 16.971

7.  Construction of an approximately 700-kb transcript map around the familial Mediterranean fever locus on human chromosome 16p13.3.

Authors:  M Centola; X Chen; R Sood; Z Deng; I Aksentijevich; T Blake; D O Ricke; X Chen; G Wood; N Zaks; N Richards; D Krizman; E Mansfield; S Apostolou; J Liu; N Shafran; A Vedula; M Hamon; A Cercek; T Kahan; D Gumucio; D F Callen; R I Richards; R K Moyzis; N A Doggett; F S Collins; P P Liu; N Fischel-Ghodsian; D L Kastner
Journal:  Genome Res       Date:  1998-11       Impact factor: 9.043

8.  A 1.5-megabase yeast artificial chromosome contig from human chromosome 10q11.2 connecting three genetic loci (RET, D10S94, and D10S102) closely linked to the MEN2A locus.

Authors:  T C Lairmore; S Dou; J R Howe; D Chi; K Carlson; R Veile; S K Mishra; S A Wells; H Donis-Keller
Journal:  Proc Natl Acad Sci U S A       Date:  1993-01-15       Impact factor: 11.205

9.  Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19.

Authors:  M F Rousseau-Merck; J Hillion; P Jonveaux; P Couillin; P Seité; H J Thiesen; R Berger
Journal:  Hum Genet       Date:  1993-12       Impact factor: 4.132

10.  Human zinc finger gene ZNF23 (Kox16) maps to a zinc finger gene cluster on chromosome 16q22, and ZNF32 (Kox30) to chromosome region 10q23-q24.

Authors:  L A Cannizzaro; M M Aronson; H J Thiesen
Journal:  Hum Genet       Date:  1993-05       Impact factor: 4.132

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