Literature DB >> 16392090

Efavirenz and CYP2B6 polymorphism: implications for drug toxicity and resistance.

David Nolan, Elizabeth Phillips, Simon Mallal.   

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Year:  2005        PMID: 16392090     DOI: 10.1086/499369

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


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  13 in total

1.  Long-term efficacy and safety of efavirenz dose reduction to 200 mg once daily in a Caucasian patient with HIV.

Authors:  Salvador Cabrera Figueroa; Alicia Iglesias Gómez; Almudena Sánchez Martín; María de la Paz Valverde Merino; Alfonso Domínguez-Gil Hurlé; Miguel Cordero Sánchez
Journal:  Clin Drug Investig       Date:  2010       Impact factor: 2.859

Review 2.  Efavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and Stereochemistry.

Authors:  Pan-Fen Wang; Alicia Neiner; Evan D Kharasch
Journal:  Drug Metab Dispos       Date:  2019-07-19       Impact factor: 3.922

Review 3.  PharmGKB summary: Efavirenz pathway, pharmacokinetics.

Authors:  Ellen M McDonagh; Johnathan L Lau; Maria L Alvarellos; Russ B Altman; Teri E Klein
Journal:  Pharmacogenet Genomics       Date:  2015-07       Impact factor: 2.089

4.  Rapid clinical induction of hepatic cytochrome P4502B6 activity by ritonavir.

Authors:  Evan D Kharasch; Darain Mitchell; Rebecka Coles; Roberto Blanco
Journal:  Antimicrob Agents Chemother       Date:  2008-02-19       Impact factor: 5.191

5.  Low level of efavirenz in HIV-1-infected Thai adults is associated with the CYP2B6 polymorphism.

Authors:  C Sukasem; W Manosuthi; N Koomdee; S Santon; T Jantararoungtong; S Prommas; M Chamnanphol; A Puangpetch; S Sungkanuparph
Journal:  Infection       Date:  2013-11-30       Impact factor: 3.553

Review 6.  CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme.

Authors:  Hongbing Wang; Leslie M Tompkins
Journal:  Curr Drug Metab       Date:  2008-09       Impact factor: 3.731

7.  Stereoselective metabolism of bupropion by cytochrome P4502B6 (CYP2B6) and human liver microsomes.

Authors:  Rebecka Coles; Evan D Kharasch
Journal:  Pharm Res       Date:  2008-06       Impact factor: 4.200

8.  Induction of cytochrome P450 2B6 activity by the herbal medicine baicalin as measured by bupropion hydroxylation.

Authors:  Lan Fan; Jin-Chao Wang; Feng Jiang; Zhi-Rong Tan; Yao Chen; Qing Li; Wei Zhang; Guo Wang; He-Ping Lei; Dong-Li Hu; Dan Wang; Hong-Hao Zhou
Journal:  Eur J Clin Pharmacol       Date:  2008-12-09       Impact factor: 2.953

9.  Use of enantiomeric bupropion and hydroxybupropion to assess CYP2B6 activity in glomerular kidney diseases.

Authors:  Melanie S Joy; Reginald F Frye; Kristi Stubbert; Kim R Brouwer; Ronald J Falk; Evan D Kharasch
Journal:  J Clin Pharmacol       Date:  2010-01-26       Impact factor: 3.126

10.  Case report: Severe central nervous system manifestations associated with aberrant efavirenz metabolism in children: the role of CYP2B6 genetic variation.

Authors:  Francoise Pinillos; Collet Dandara; Marelize Swart; Renate Strehlau; Louise Kuhn; Faeezah Patel; Ashraf Coovadia; Elaine Abrams
Journal:  BMC Infect Dis       Date:  2016-02-02       Impact factor: 3.090

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