Literature DB >> 25966836

PharmGKB summary: Efavirenz pathway, pharmacokinetics.

Ellen M McDonagh1, Johnathan L Lau, Maria L Alvarellos, Russ B Altman, Teri E Klein.   

Abstract

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Year:  2015        PMID: 25966836      PMCID: PMC4461466          DOI: 10.1097/FPC.0000000000000145

Source DB:  PubMed          Journal:  Pharmacogenet Genomics        ISSN: 1744-6872            Impact factor:   2.089


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  61 in total

1.  Tribal ethnicity and CYP2B6 genetics in Ugandan and Zimbabwean populations in the UK: implications for efavirenz dosing in HIV infection.

Authors:  Y Jamshidi; M Moreton; D A McKeown; S Andrews; T Nithiyananthan; L Tinworth; D W Holt; S T Sadiq
Journal:  J Antimicrob Chemother       Date:  2010-10-14       Impact factor: 5.790

2.  Long-term efavirenz autoinduction and its effect on plasma exposure in HIV patients.

Authors:  E Ngaimisi; S Mugusi; O M Minzi; P Sasi; K-D Riedel; A Suda; N Ueda; M Janabi; F Mugusi; W E Haefeli; J Burhenne; E Aklillu
Journal:  Clin Pharmacol Ther       Date:  2010-09-29       Impact factor: 6.875

3.  CYP2B6 983T>C polymorphism is prevalent in West Africa but absent in Papua New Guinea: implications for HIV/AIDS treatment.

Authors:  Rajeev K Mehlotra; Moses J Bockarie; Peter A Zimmerman
Journal:  Br J Clin Pharmacol       Date:  2007-03-28       Impact factor: 4.335

4.  Are plasma levels valid surrogates for cellular concentrations of antiretroviral drugs in HIV-infected patients?

Authors:  Sara Colombo; Amalio Telenti; Thierry Buclin; Hansjakob Furrer; Belle L Lee; Jérôme Biollaz; Laurent A Decosterd
Journal:  Ther Drug Monit       Date:  2006-06       Impact factor: 3.681

5.  Identification and characterization of efavirenz metabolites by liquid chromatography/mass spectrometry and high field NMR: species differences in the metabolism of efavirenz.

Authors:  A E Mutlib; H Chen; G A Nemeth; J A Markwalder; S P Seitz; L S Gan; D D Christ
Journal:  Drug Metab Dispos       Date:  1999-11       Impact factor: 3.922

6.  Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients.

Authors:  Abiy Habtewold; Wondwossen Amogne; Eyasu Makonnen; Getnet Yimer; Klaus-Dieter Riedel; Nobuhisa Ueda; Alemayehu Worku; Walter Emil Haefeli; Lars Lindquist; Getachew Aderaye; Jürgen Burhenne; Eleni Aklillu
Journal:  J Antimicrob Chemother       Date:  2011-08-16       Impact factor: 5.790

7.  Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study.

Authors:  David W Haas; Laura M Smeaton; Robert W Shafer; Gregory K Robbins; Gene D Morse; Line Labbe; Grant R Wilkinson; David B Clifford; Richard T D'Aquila; Victor De Gruttola; Richard B Pollard; Thomas C Merigan; Martin S Hirsch; Alfred L George; John P Donahue; Richard B Kim
Journal:  J Infect Dis       Date:  2005-11-01       Impact factor: 5.226

8.  Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes.

Authors:  David W Haas; Awewura Kwara; Danielle M Richardson; Paxton Baker; Ioannis Papageorgiou; Edward P Acosta; Gene D Morse; Michael H Court
Journal:  J Antimicrob Chemother       Date:  2014-04-11       Impact factor: 5.790

9.  Pharmacogenetics and clinical biomarkers for subtherapeutic plasma efavirenz concentration in HIV-1 infected Thai adults.

Authors:  Chonlaphat Sukasem; Montri Chamnanphon; Napatrupron Koomdee; Siwalee Santon; Thawinee Jantararoungtong; Santirat Prommas; Apichaya Puangpetch; Weerawat Manosuthi
Journal:  Drug Metab Pharmacokinet       Date:  2014-01-28       Impact factor: 3.614

10.  Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine.

Authors:  Melissa A Frasco; Wendy J Mack; David Van Den Berg; Bradley E Aouizerat; Kathryn Anastos; Mardge Cohen; Jack De Hovitz; Elizabeth T Golub; Ruth M Greenblatt; Chenglong Liu; David V Conti; Celeste L Pearce
Journal:  AIDS       Date:  2012-10-23       Impact factor: 4.177

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  14 in total

1.  Brief Report: Rate of Nicotine Metabolism and Tobacco Use Among Persons With HIV: Implications for Treatment and Research.

Authors:  Robert A Schnoll; Morgan Thompson; Katrina Serrano; Frank Leone; David Metzger; Ian Frank; Robert Gross; Karam Mounzer; Rachel F Tyndale; Jessica Weisbrot; Miles Meline; Ronald G Collman; Rebecca L Ashare
Journal:  J Acquir Immune Defic Syndr       Date:  2019-02-01       Impact factor: 3.731

2.  Differences in the rate of nicotine metabolism among smokers with and without HIV.

Authors:  Rebecca L Ashare; Morgan Thompson; Frank Leone; David Metzger; Robert Gross; Karam Mounzer; Rachel F Tyndale; Caryn Lerman; Martin C Mahoney; Paul Cinciripini; Tony P George; Ronald G Collman; Robert Schnoll
Journal:  AIDS       Date:  2019-05-01       Impact factor: 4.177

3.  Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz-Containing Antiretroviral Therapy.

Authors:  Zeruesenay Desta; Roseann S Gammal; Li Gong; Michelle Whirl-Carrillo; Aditya H Gaur; Chonlaphat Sukasem; Jennifer Hockings; Alan Myers; Marelize Swart; Rachel F Tyndale; Collen Masimirembwa; Otito F Iwuchukwu; Sanika Chirwa; Jeffrey Lennox; Andrea Gaedigk; Teri E Klein; David W Haas
Journal:  Clin Pharmacol Ther       Date:  2019-07-05       Impact factor: 6.875

Review 4.  Pharmacogenetics and Precision Medicine Approaches for the Improvement of COVID-19 Therapies.

Authors:  Mohitosh Biswas; Nares Sawajan; Thanyada Rungrotmongkol; Kamonpan Sanachai; Maliheh Ershadian; Chonlaphat Sukasem
Journal:  Front Pharmacol       Date:  2022-02-18       Impact factor: 5.810

Review 5.  Bidirectional Associations among Nicotine and Tobacco Smoke, NeuroHIV, and Antiretroviral Therapy.

Authors:  Shivesh Ghura; Robert Gross; Kelly Jordan-Sciutto; Jacob Dubroff; Robert Schnoll; Ronald G Collman; Rebecca L Ashare
Journal:  J Neuroimmune Pharmacol       Date:  2019-12-13       Impact factor: 4.147

6.  Pharmacokinetics and phenotyping properties of the Basel phenotyping cocktail combination capsule in healthy male adults.

Authors:  Claudia Suenderhauf; Benjamin Berger; Maxim Puchkov; Yasmin Schmid; Sabine Müller; Jörg Huwyler; Manuel Haschke; Stephan Krähenbühl; Urs Duthaler
Journal:  Br J Clin Pharmacol       Date:  2019-12-12       Impact factor: 4.335

7.  Brief Report: Nicotine Metabolism Ratio Increases in HIV-Positive Smokers on Effective Antiretroviral Therapy: A Cohort Study.

Authors:  Cedric H Bien-Gund; Warren Bilker; Robert A Schnoll; Rachel F Tyndale; Joshua I Ho; Remy Bremner; Rebecca L Ashare; Robert Gross
Journal:  J Acquir Immune Defic Syndr       Date:  2022-04-01       Impact factor: 3.771

8.  Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype.

Authors:  Eliford Ngaimisi Kitabi; Omary Mashiku Sylivester Minzi; Sabina Mugusi; Philip Sasi; Mohamed Janabi; Ferdinand Mugusi; Leif Bertilsson; Jürgen Burhenne; Eleni Aklillu
Journal:  Sci Rep       Date:  2018-11-05       Impact factor: 4.379

9.  Tryptophan metabolism and its relationship with central nervous system toxicity in people living with HIV switching from efavirenz to dolutegravir.

Authors:  Michael R Keegan; Alan Winston; Chris Higgs; Dietmar Fuchs; Adriano Boasso; Mark Nelson
Journal:  J Neurovirol       Date:  2018-11-26       Impact factor: 2.643

10.  Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans.

Authors:  Andreas Schittny; Samuel Waldner; Urs Duthaler; Alexander Vorobyev; Rimma Abramovich; Stephan Krähenbühl; Maxim Puchkov; Jörg Huwyler
Journal:  Pharmaceutics       Date:  2021-03-17       Impact factor: 6.321

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