Literature DB >> 16391136

The Bifidobacterium longum NCIMB 702259T ctr gene codes for a novel cholate transporter.

Claire E Price1, Sharon J Reid, Arnold J M Driessen, Valerie R Abratt.   

Abstract

Preexposure of Bifidobacterium longum NCIMB 702259T to cholate caused increased resistance to cholate, chloramphenicol, and erythromycin. The B. longum ctr gene, encoding a cholate efflux transporter, was transformed into the efflux-negative mutant Escherichia coli KAM3, conferring resistance to bile salts and other antimicrobial compounds and causing the efflux of [14C]cholate.

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Year:  2006        PMID: 16391136      PMCID: PMC1352250          DOI: 10.1128/AEM.72.1.923-926.2006

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN: 0099-2240            Impact factor:   4.792


  15 in total

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