BACKGROUND: There are numerous potential sources of problems when performing complex clinical research trials. These issues are compounded when studies are multi-site and multiple personnel from different sites are responsible for varying actions from case report form design to primary data collection and data entry. METHODS: We describe an approach that emphasizes the use of a variety of informatics tools that can facilitate study coordination, training, data checks and early identification and correction of faulty procedures and data problems. The paper focuses on informatics tools that can help in case report form design, procedures and training and data management. CONCLUSION: Informatics tools can be used to facilitate study coordination and implementation of clinical research trials.
BACKGROUND: There are numerous potential sources of problems when performing complex clinical research trials. These issues are compounded when studies are multi-site and multiple personnel from different sites are responsible for varying actions from case report form design to primary data collection and data entry. METHODS: We describe an approach that emphasizes the use of a variety of informatics tools that can facilitate study coordination, training, data checks and early identification and correction of faulty procedures and data problems. The paper focuses on informatics tools that can help in case report form design, procedures and training and data management. CONCLUSION: Informatics tools can be used to facilitate study coordination and implementation of clinical research trials.
Authors: Andrew D Boyd; Paul R Saxman; Dale A Hunscher; Kevin A Smith; Timothy D Morris; Michelle Kaston; Frederick Bayoff; Bruce Rogers; Pamela Hayes; Namrata Rajeev; Eva Kline-Rogers; Kim Eagle; Daniel Clauw; John F Greden; Lee A Green; Brian D Athey Journal: J Am Med Inform Assoc Date: 2009-08-28 Impact factor: 4.497
Authors: Steven R Offerman; Adina S Rauchwerger; Daniel K Nishijima; Dustin W Ballard; Uli K Chettipally; David R Vinson; Mary E Reed; James F Holmes Journal: West J Emerg Med Date: 2013-03
Authors: Joanna Reynolds; Deborah DiLiberto; Lindsay Mangham-Jefferies; Evelyn K Ansah; Sham Lal; Hilda Mbakilwa; Katia Bruxvoort; Jayne Webster; Lasse S Vestergaard; Shunmay Yeung; Toby Leslie; Eleanor Hutchinson; Hugh Reyburn; David G Lalloo; David Schellenberg; Bonnie Cundill; Sarah G Staedke; Virginia Wiseman; Catherine Goodman; Clare I R Chandler Journal: Implement Sci Date: 2014-06-17 Impact factor: 7.327