| Literature DB >> 16386422 |
Hidenori Takahashi1, Younes Bekkali, Alison J Capolino, Thomas Gilmore, Susan E Goldrick, Richard M Nelson, Donna Terenzio, Ji Wang, Ljiljana Zuvela-Jelaska, John Proudfoot, Gerald Nabozny, David Thomson.
Abstract
We report the discovery of a novel class of glucocorticoid receptor (GR) ligands based on 1,2-dihydroquinoline molecular scaffold. The compounds exhibit good GR binding affinity and selectivity profile against other nuclear hormone receptors.Entities:
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Year: 2005 PMID： 16386422 DOI： 10.1016/j.bmcl.2005.12.043
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823