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Literature DB >> 16378367

Sesquiterpenoids and norsesquiterpenoids from the Formosan soft coral Lemnalia laevis.

Ali A H El-Gamal¹, E-Ping Chiu, Chia-Hua Li, Shi-Yie Cheng, Chang-Feng Dai, Chang-Yih Duh.

Abstract

Eight new nornardosinane sequiterpenoids, laevinols A-H (1-8), a new neolemnane sesquiterpenoid, laevinone A (9), and the previously known 6beta-acetyl-4beta,5beta-dimethyl-1(10)alpha-epoxy-2beta-hydroxy-7-oxodecalin (10) and 11,12-dihydroxy-6,10-eremophiladiene (11) were isolated from the methylene chloride solubles of the Formosan soft coral Lemnalia laevis. Their structures were elucidated by extensive spectroscopic analysis, and their cytotoxicity against selected cancer cells was measured in vitro.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2005 PMID： 16378367 DOI： 10.1021/np050326r

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

6 in total

1. Chemical and biological studies on the soft coral Nephthea sp.

Authors: Omnia Hesham Abdelhafez; John Refaat Fahim; Ramy R El Masri; M Alaraby Salem; Samar Yehia Desoukey; Safwat Ahmed; Mohamed Salah Kamel; Sheila Marie Pimentel-Elardo; Justin R Nodwell; Usama Ramadan Abdelmohsen
Journal: RSC Adv Date: 2021-07-05 Impact factor: 4.036

2. (1R,2S,4S,4aS,8S,8aS)-4-Hy-droxy-8,8a-dimethyl-10-oxo-2,3,4,7,8,8a-hexa-hydro-1H-4a,1-(ep-oxy-methano)-naphthalen-2-yl acetate.

Authors: Ouassila Selaïmia-Ferdjani; Chahra Bidjou-Haiour; Aurelien Planchat; Muriel Pipelier
Journal: Acta Crystallogr Sect E Struct Rep Online Date: 2013-05-22

Sesquiterpenoids and norsesquiterpenoids from the Formosan soft coral Lemnalia laevis.

1. Chemical and biological studies on the soft coral Nephthea sp.

2. (1R,2S,4S,4aS,8S,8aS)-4-Hy-droxy-8,8a-dimethyl-10-oxo-2,3,4,7,8,8a-hexa-hydro-1H-4a,1-(ep-oxy-methano)-naphthalen-2-yl acetate.

3. nardosinane-type sesquiterpenoids from the formosan soft coral Paralemnalia thyrsoides.

4. Antimicrobial Terpenoids from South China Sea Soft Coral Lemnalia sp.

5. Oxygenated eremophilane- and neolemnane-derived sesquiterpenoids from the soft coral Lemnalia philippinensis.

Review 6. Terpenoids from Marine Soft Coral of the Genus Lemnalia: Chemistry and Biological Activities.