Literature DB >> 16377184

Natural and synthetic G-quadruplex interactive berberine derivatives.

Marco Franceschin1, Luigi Rossetti, Anna D'Ambrosio, Stefano Schirripa, Armandodoriano Bianco, Giancarlo Ortaggi, Maria Savino, Christoph Schultes, Stephen Neidle.   

Abstract

The interaction of the natural alkaloid berberine with various G-quadruplex DNA structures and its ability to inhibit telomerase have been examined and compared with those of a synthetic piperidino derivative and the related compound coralyne. The results show that these molecules have selectivity for G-quadruplex compared to duplex DNA, and that their aromatic moieties play a dominant role in quadruplex binding.

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Year:  2006        PMID： 16377184     DOI： 10.1016/j.bmcl.2005.12.001

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  39 in total

1.  The Hairpin Form of r(G4C2)exp in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules.

Authors:  Zi-Fu Wang; Andrei Ursu; Jessica L Childs-Disney; Rea Guertler; Wang-Yong Yang; Viachaslau Bernat; Suzanne G Rzuczek; Rita Fuerst; Yong-Jie Zhang; Tania F Gendron; Ilyas Yildirim; Brendan G Dwyer; Joseph E Rice; Leonard Petrucelli; Matthew D Disney
Journal:  Cell Chem Biol       Date:  2018-11-29       Impact factor: 8.116

2.  Use of competition dialysis in the discovery of G-quadruplex selective ligands.

Authors:  Patricia Ragazzon; Jonathan B Chaires
Journal:  Methods       Date:  2007-12       Impact factor: 3.608

3.  Molecular Recognition of the Hybrid-2 Human Telomeric G-Quadruplex by Epiberberine: Insights into Conversion of Telomeric G-Quadruplex Structures.

Authors:  Clement Lin; Guanhui Wu; Kaibo Wang; Buket Onel; Saburo Sakai; Yong Shao; Danzhou Yang
Journal:  Angew Chem Int Ed Engl       Date:  2018-07-18       Impact factor: 15.336

4.  Pyridine Derivative of the Natural Alkaloid Berberine as Human Telomeric G4-DNA Binder: A Solution and Solid-State Study.

Authors:  Francesco Papi; Carla Bazzicalupi; Marta Ferraroni; Giulia Ciolli; Paolo Lombardi; Asma Yasmeen Khan; Gopinatha Suresh Kumar; Paola Gratteri
Journal:  ACS Med Chem Lett       Date:  2020-02-07       Impact factor: 4.345

5.  Aminoglycoside binding to Oxytricha nova telomeric DNA.

Authors:  Nihar Ranjan; Katrine F Andreasen; Sunil Kumar; David Hyde-Volpe; Dev P Arya
Journal:  Biochemistry       Date:  2010-10-22       Impact factor: 3.162

6.  Raman spectrum spectral imaging revealing the molecular mechanism of Berberine-induced Jurkat cell apoptosis and the receptor-mediated Berberine delivery system.

Authors:  Ping Tang; Wendai Cheng; Xuanmeng He; Qinnan Zhang; Jing Zhong; Xiaoxu Lu; Shengde Liu; Liyun Zhong
Journal:  Biomed Opt Express       Date:  2019-03-04       Impact factor: 3.732

7.  Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer.

Authors:  Motilal Maiti; Gopinatha Suresh Kumar
Journal:  J Nucleic Acids       Date:  2009-12-15

8.  A 'light-up' intercalator displacement assay for detection of triplex DNA stabilizers.

Authors:  Imee M A Del Mundo; Eun Jeong Cho; Kevin N Dalby; Karen M Vasquez
Journal:  Chem Commun (Camb)       Date:  2020-02-13       Impact factor: 6.222

Review 9.  Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes.

Authors:  Bruno Pagano; Carlo Andrea Mattia; Concetta Giancola
Journal:  Int J Mol Sci       Date:  2009-07-02       Impact factor: 6.208

10.  New aspects of the interaction of the antibiotic coralyne with RNA: coralyne induces triple helix formation in poly(rA)*poly(rU).

Authors:  Tarita Biver; Alessia Boggioni; Begoña García; José M Leal; Rebeca Ruiz; Fernando Secco; Marcella Venturini
Journal:  Nucleic Acids Res       Date:  2009-12-14       Impact factor: 16.971
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