PURPOSE: To evaluate a noninvasive technique to detect the leakage point of central serous chorioretinopathy (CSR), using a polarimetry method. DESIGN: Prospective cohort study. SETTING: Institutional practice. PATIENTS: We examined 30 eyes of 30 patients with CSR. MAIN OUTCOME MEASURES: Polarimetry images were recorded using the GDx-N (Laser Diagnostic Technologies). We computed four images that differed in their polarization content: a depolarized light image, an average reflectance image, a parallel polarized light image, and a birefringence image. Each polarimetry image was compared with abnormalities seen on fluorescein angiography. RESULTS: In all eyes, leakage area could be clearly visualized as a bright area in the depolarized light images. Michelson contrasts for the leakage areas were 0.58 +/- 0.28 in the depolarized light images, 0.17 +/- 0.11 in the average reflectance images, 0.09 +/- 0.09 in the parallel polarized light images, and 0.11 +/- 0.21 in the birefringence images from the same raw data. Michelson contrasts in depolarized light images were significantly higher than for the other three images (P < .0001, for all tests, paired t test). The fluid accumulated in the retina was well-visualized in the average and parallel polarized light images. CONCLUSIONS: Polarization-sensitive imaging could readily localize the leakage point and area of fluid in CSR. This may assist with the rapid, noninvasive assessment of CSR.
PURPOSE: To evaluate a noninvasive technique to detect the leakage point of central serous chorioretinopathy (CSR), using a polarimetry method. DESIGN: Prospective cohort study. SETTING: Institutional practice. PATIENTS: We examined 30 eyes of 30 patients with CSR. MAIN OUTCOME MEASURES: Polarimetry images were recorded using the GDx-N (Laser Diagnostic Technologies). We computed four images that differed in their polarization content: a depolarized light image, an average reflectance image, a parallel polarized light image, and a birefringence image. Each polarimetry image was compared with abnormalities seen on fluorescein angiography. RESULTS: In all eyes, leakage area could be clearly visualized as a bright area in the depolarized light images. Michelson contrasts for the leakage areas were 0.58 +/- 0.28 in the depolarized light images, 0.17 +/- 0.11 in the average reflectance images, 0.09 +/- 0.09 in the parallel polarized light images, and 0.11 +/- 0.21 in the birefringence images from the same raw data. Michelson contrasts in depolarized light images were significantly higher than for the other three images (P < .0001, for all tests, paired t test). The fluid accumulated in the retina was well-visualized in the average and parallel polarized light images. CONCLUSIONS: Polarization-sensitive imaging could readily localize the leakage point and area of fluid in CSR. This may assist with the rapid, noninvasive assessment of CSR.
Authors: Masahiro Miura; Anne E Elsner; Eva Beausencourt; Christian Kunze; M Elzabeth Hartnett; Kameran Lashkari; Clement L Trempe Journal: Retina Date: 2002-06 Impact factor: 4.256
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Authors: Andrea von Rückmann; Frederick W Fitzke; Joseph Fan; Anthony Halfyard; Alan C Bird Journal: Am J Ophthalmol Date: 2002-06 Impact factor: 5.258
Authors: Masahiro Miura; Ann E Elsner; Michael C Cheney; Masahiko Usui; Takuya Iwasaki Journal: J Opt Soc Am A Opt Image Sci Vis Date: 2007-05 Impact factor: 2.129
Authors: Ann E Elsner; Anke Weber; Michael C Cheney; Dean A VanNasdale; Masahiro Miura Journal: J Opt Soc Am A Opt Image Sci Vis Date: 2007-05 Impact factor: 2.129
Authors: Dean A VanNasdale; Ann E Elsner; Todd D Peabody; Kimberly D Kohne; Victor E Malinovsky; Bryan P Haggerty; Anke Weber; Christopher A Clark; Stephen A Burns Journal: Invest Ophthalmol Vis Sci Date: 2014-12-18 Impact factor: 4.799