| Literature DB >> 16376261 |
William L Walter1, Jonathan Clabeaux, Timothy M Wright, William Walsh, William K Walter, Thomas P Sculco.
Abstract
The pumping of fluid and polyethylene wear debris from the joint space to the retroacetabular bone is implicated in the pathogenesis of osteolysis. Three possible mechanisms for this pumping: pressure gradients, diaphragm pumping, and piston pumping were studied in vitro in a laboratory model. The simulated activities of rising from a chair and climbing stairs produced high-pressure gradients and high angles of loading that could pump fluid through the apical hole to the retroacetabular bone. A noncongruent liner acted as a diaphragm pump, producing pressures 6 times higher than that seen with a congruent liner. Pistoning motion of the liner produced pressures 8 times higher than when no pistoning occurs. These pumping mechanisms could be mitigated by the use of acetabular components without holes.Entities:
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Year: 2005 PMID: 16376261 DOI: 10.1016/j.arth.2005.03.039
Source DB: PubMed Journal: J Arthroplasty ISSN: 0883-5403 Impact factor: 4.757