Literature DB >> 1637505

Preferred positions of AA and TT dinucleotides in aligned nucleosomal DNA sequences.

I Ioshikhes1, A Bolshoy, E N Trifonov.   

Abstract

Multiple alignment of 118 nucleosomal DNA sequences by maximizing simultaneously match of AA dinucleotides and match of TT dinucleotides results in a pattern of the dinucleotide distributions which is characteristic of the nucleosomal DNA sequences. The AA dinucleotides are found to be distributed symmetrically relative to the TT dinucleotide distribution, around the middle point of the nucleosomal DNA sequence. The distances between major peaks of the distributions are multiples of about 10.4 bases. The peaks of the TT distribution are shifted by 6 bases downstream from the peaks of the AA distribution.

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Year:  1992        PMID: 1637505     DOI: 10.1080/07391102.1992.10507982

Source DB:  PubMed          Journal:  J Biomol Struct Dyn        ISSN: 0739-1102


  8 in total

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