Literature DB >> 16372529

Early results from a phase I study on orally administered tris(8-quinolinolato)gallium(III) (FFC11, KP46) in patients with solid tumors--a CESAR study (Central European Society for Anticancer Drug Research--EWIV).

R D Hofheinz1, C Dittrich, M A Jakupec, A Drescher, U Jaehde, M Gneist, N Graf von Keyserlingk, B K Keppler, A Hochhaus.   

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Year:  2005        PMID： 16372529     DOI： 10.5414/cpp43590

Source DB:  PubMed          Journal:  Int J Clin Pharmacol Ther        ISSN： 0946-1965            Impact factor:   1.366


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  13 in total

1.  Interaction of the anticancer gallium(III) complexes of 8-hydroxyquinoline and maltol with human serum proteins.

Authors:  Éva A Enyedy; Orsolya Dömötör; Krisztina Bali; Anasztázia Hetényi; Tiziano Tuccinardi; Bernhard K Keppler
Journal:  J Biol Inorg Chem       Date:  2014-11-15       Impact factor: 3.358

2.  A novel gallium compound synergistically enhances bortezomib-induced apoptosis in mantle cell lymphoma cells.

Authors:  Christopher R Chitambar; David P Purpi
Journal:  Leuk Res       Date:  2010-03-24       Impact factor: 3.156

Review 3.  Gallium-containing anticancer compounds.

Authors:  Christopher R Chitambar
Journal:  Future Med Chem       Date:  2012-06       Impact factor: 3.808

4.  New heteroleptic oxidovanadium(V) complexes: synthesis, characterization and biological evaluation as potential agents against Trypanosoma cruzi.

Authors:  Gonzalo Scalese; Ignacio Machado; Carolina Fontana; Gastón Risi; Gustavo Salinas; Leticia Pérez-Díaz; Dinorah Gambino
Journal:  J Biol Inorg Chem       Date:  2018-09-08       Impact factor: 3.358

5.  Biological study of the effect of water soluble [N-(2-hydroxybenzyl)-L-aspartato] gallium complexes on breast carcinoma and fibrosarcoma cells.

Authors:  Ahmed Mohsen; Charles Saby; Philippe Collery; Gilane Mohamed Sabry; Rasha Elsherif Hassan; Abdelfattah Badawi; Pierre Jeannesson; Didier Desmaële; Hamid Morjani
Journal:  J Biol Inorg Chem       Date:  2016-08-02       Impact factor: 3.358

6.  Cytotoxicity, apoptosis and study of the DNA-binding properties of bi- and tetranuclear gallium(III) complexes with heterocyclic thiolato ligands.

Authors:  Beatriz Gallego; Milena R Kaluđerović; Harish Kommera; Reinhard Paschke; Evamarie Hey-Hawkins; Torsten W Remmerbach; Goran N Kaluđerović; Santiago Gómez-Ruiz
Journal:  Invest New Drugs       Date:  2010-05-15       Impact factor: 3.850

7.  Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs.

Authors:  Ekaterina Schreiber-Brynzak; Erik Klapproth; Christine Unger; Irene Lichtscheidl-Schultz; Simone Göschl; Sarah Schweighofer; Robert Trondl; Helmut Dolznig; Michael A Jakupec; Bernhard K Keppler
Journal:  Invest New Drugs       Date:  2015-06-21       Impact factor: 3.850

Review 8.  Iron-targeting antitumor activity of gallium compounds and novel insights into triapine(®)-metal complexes.

Authors:  Christopher R Chitambar; William E Antholine
Journal:  Antioxid Redox Signal       Date:  2012-10-03       Impact factor: 8.401

Review 9.  Medical applications and toxicities of gallium compounds.

Authors:  Christopher R Chitambar
Journal:  Int J Environ Res Public Health       Date:  2010-05-10       Impact factor: 3.390

10.  The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines.

Authors:  Seied Mojtaba Valiahdi; Petra Heffeter; Michael A Jakupec; Rodrig Marculescu; Walter Berger; Klemens Rappersberger; Bernhard K Keppler
Journal:  Melanoma Res       Date:  2009-10       Impact factor: 3.599
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